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Merck
CN

05-903

Anti-GSK3α/β Antibody, rabbit monoclonal

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
monoclonal
Application:
IP, WB
Citations:
14
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GSK3A(2931)

General description

Mr 46kDa (beta) and 51kDa (alpha)

Immunogen

N-terminal 6His-tagged recombinant full length human GSK3β

Application

Anti-GSK3α/β Antibody is an antibody against GSK3α/β for use in IP & WB.

Biochem/physiol Actions

GSK3 alpha and beta
Predicted to cross-react with rat based on sequence homology

Physical form

Format: Purified

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
routinely evaluated by immunoblot on lysates from HEK293 cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

10 - Combustible liquids

wgk

WGK 1



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes.
Jope, Richard S
Trends in Pharmacological Sciences, 24, 441-443 (2003)
GSK-3: tricks of the trade for a multi-tasking kinase.
Doble, Bradley W and Woodgett, James R
Journal of Cell Science, 116, 1175-1186 (2003)
Jen Q Pan et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 36(7), 1397-1411 (2011-03-11)
Bipolar disorder (BP) is a debilitating psychiatric disorder, affecting ∼2% of the worldwide population, for which the etiological basis, pathogenesis, and neurocircuitry remain poorly understood. Individuals with BP suffer from recurrent episodes of mania and depression, which are commonly treated



Global Trade Item Number

SKUGTIN
05-90304053252477843