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Merck
CN

16-125

Protein A Agarose

Protein A Agarose Beads for the purification of human, mouse & rabbit immunoglobins.

Synonym(s):

Protein A resin

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About This Item

UNSPSC Code:
41116133
NACRES:
NA.56
eCl@ss:
32160801
Form:
liquid
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form

liquid

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

shipped in

wet ice

General description

Protein A affinity adsorbent possessing a high antibody-binding capacity is significantly used for the purification of biopharmaceuticals. Protein A agarose beads contain sufficient covalently-linked Protein A for a binding capacity of 20+/-2 milligrams human IgG per 1 milliliter.

Application

Protein A Agarose has been used in immunoprecipitation. It is suitable for the purification of human, mouse, and rabbit immunoglobulins.

Physical form

water containing 0.01% thimerosal

Preparation Note

1 year at 4°C

Analysis Note

routinely evaluated by immunoprecipitating phosphotyrosine containing proteins from an EGF-stimulated A431 cell lysate with Anti-Phosphotyrosine antibody (05-321)

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

pictograms

Flame

signalword

Danger

hcodes

Hazard Classifications

Flam. Liq. 2



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Pertussis toxin-sensitive G proteins as mediators of the signal transduction pathways activated by cytomegalovirus infection of smooth muscle cells.
Shibutani, T, et al.
The Journal of Clinical Investigation, 100, 2054-2061 (1997)
Paola Sacchetti et al.
Nucleic acids research, 34(19), 5515-5527 (2006-10-06)
The orphan nuclear receptor nurr1 (NR4A2) is an essential transcription factor for the acquisition and maintenance of the phenotype of dopamine (DA)-synthesizing neurons in the mesencephalon. Although structurally related to ligand-regulated nuclear receptors, nurr1 is functionally atypical due to its
Activation of endothelin ETA receptors induces phosphorylation of alpha1b-adrenoreceptors in Rat-1 fibroblasts
Vazquez-Prado, J., et al
The Journal of Biological Chemistry, 272, 27330-27337 (1997)



Global Trade Item Number

SKUGTIN
16-12504053252627903
MABC1608-25UG04054839437885
RAB0376-1KT04061834962076
MABC160804054839355615
CLS7082016X-50EA04061831704198
CLS7082016X-200EA04061831704181
CLS7082516X-200EA04061831710724
CLS982516X-144EA04061831705997
CLS982516X-288EA04061831706000
CLS982616X-288EA04061831706109
CLS986016-288EA04061831706154
CLS986016-72EA04061831676273
CLS982616X-144EA04061831706093
BR114120-105EA04061831845631
Z741003-200EA04061833635162
Z741004-50EA04061833641798
Z740988-50EA04061833641712
DWK73500-1612504061841117926
DWK90K16125F04061841118565
DWK73750-1612504061841118268
DWK73760-1612504061841118305
CLS430157-500EA04061833887219