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495414

1-Oleoyl-2-acetyl-sn-glycerol

Name: 1-Oleoyl-2-acetyl-<i>sn</i>-glycerol
Brand: MM

≥97% (HPLC), Ca²⁺-dependent protein kinase C activator, oil

Synonym(s):

1-Oleoyl-2-acetyl-sn-glycerol, OAG, PKC Activator III

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₄₂O₅

CAS Number:

86390-77-4

Molecular Weight:

398.58

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00166985

Assay:

≥97% (HPLC)

Form:

oil

Quality level:

100

Storage condition:

OK to freeze

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Properties

Product Name

1-Oleoyl-2-acetyl-sn-glycerol, Cell-permeable diacylglycerol analog that activates Ca²⁺-dependent protein kinase C.

Quality Level

100

assay

≥97% (HPLC)

form

oil

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

solubility

DMSO: soluble, ethanol: soluble

format

neat

shipped in

ambient

storage temp.

−20°C

SMILES string

O([C@H](COC(=O)CCCCCCC\C=C/CCCCCCCC)CO)C(=O)C

InChI

1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10-/t22-/m0/s1

InChI key

PWTCCMJTPHCGMS-YRBAHSOBSA-N

Description

General description

Cell-permeable diacylglycerol analog that activates Ca²⁺-dependent protein kinase C. Also a stimulator of secretion and aggregation in blood platelets.

Note: 1 set = 10 x 500 µg.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Ca2+-dependent protein kinase C

Product does not compete with ATP.

Reversible: no

Preparation Note

Unstable in solution; reconstitute just prior to use. The material can be dissolved in chloroform, aliquoted, dried under a stream of nitrogen, and stored at -20°C.

Other Notes

Florin-Christensen, J. 1993. Biochem. J.289, 783.
Benz, I., et al. 1992. J. Membr. Biol. 130, 183.
Haeffner, E.W., and Wittmann, U. 1992. J. Lipid Mediat.5, 237.
Gilmore, T., and Martin, G.S. 1983. Nature306, 487.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c