662045
Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb
liquid, Calbiochem®
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, rat, mouse
Application:
—
Citations:
7
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
does not contain
preservative
species reactivity
human, rat, mouse
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
dilution
(Immunoblotting (1:1000))
isotype
IgG
shipped in
wet ice
storage temp.
−70°C
target post-translational modification
unmodified
Gene Information
human ... UCP1(7350)
General description
Protein A purified rabbit polyclonal antibody. Recognizes the UCP-1 protein.
Recognizes the UCP-1 protein.
This Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb is validated for use in Immunoblotting for the detection of Uncoupling Protein-1 (UCP-1) (145-159).
Immunogen
Mouse
a synthetic peptide [(C)SHLHGIKPRYTGTYN] corresponding to amino acids 145-159 of mouse UCP1
Application
Immunoblotting (1:1000)
Physical form
In PBS.
Preparation Note
Following initial thaw, aliquot and freeze (-70°C).
Other Notes
Does not exhibit cross-reactivity with UCP2 or UCP3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
Kozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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kappa-Opioid receptors control the metabolic response to a high-energy diet in mice.
Czyzyk, et al.
Faseb Journal, 24, 1151-1159 (2018)
Laurent Vergnes et al.
The Journal of clinical endocrinology and metabolism, 101(11), 4440-4448 (2016-11-05)
Patients with pheochromocytoma (pheo) show presence of multilocular adipocytes that express uncoupling protein 1 within periadrenal (pADR) and omental (OME) fat depots. It has been hypothesized that this is due to adrenergic stimulation by catecholamines produced by the pheo tumors.
C L Plaisier et al.
Nutrition & diabetes, 2, e46-e46 (2013-03-01)
A better understanding of the processes influencing energy expenditure could provide new therapeutic strategies for reducing obesity. As the metabolic activity of the brown adipose tissue (BAT) and skeletal muscle is an important determinant of overall energy expenditure and adiposity
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 662045-100UL | 04055977261073 |