9310-OP
TRIS Hydrochloride
OmniPur® Grade, >=99.0%
Synonym(s):
Trizma® hydrochloride, Trizma, Tris(hydroxymethyl)aminomethane, TRIS HCl, TRIS hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, Tromethane hydrochloride
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About This Item
Linear Formula:
NH2C(CH2OH)3 · HCl
CAS Number:
Molecular Weight:
157.60
NACRES:
NA.25
UNSPSC Code:
12161700
Beilstein/REAXYS Number:
3675235
MDL number:
Quality Level
form
crystalline powder, needles
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
useful pH range
7.0-9.0
pKa (25 °C)
8.1
shipped in
ambient
SMILES string
Cl.NC(CO)(CO)CO
InChI
1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
InChI key
QKNYBSVHEMOAJP-UHFFFAOYSA-N
General description
Molecular Biology Grade.
260 (10%, water): ≤0.05 AU
A280 (10%, water): ≤0.05 AU
Assay: ≥99%
DNAse: none detected
Identity IR spectrum: conforms
Lead (Pb): ≤.0002%
Phosphatase: none detected
Protease: none detected
RNAse: none detected
Water (H2O): ≤0.5%
Intended for laboratory and manufacturing use only. Not for drug, food, or household use.
260 (10%, water): ≤0.05 AU
A280 (10%, water): ≤0.05 AU
Assay: ≥99%
DNAse: none detected
Identity IR spectrum: conforms
Lead (Pb): ≤.0002%
Phosphatase: none detected
Protease: none detected
RNAse: none detected
Water (H2O): ≤0.5%
Intended for laboratory and manufacturing use only. Not for drug, food, or household use.
Application
- Use of tetraethylammonium (TEA) and Tris loading for blocking TRPM7 channels in intact cells.: This study highlights the application of TRIS Hydrochloride in blocking TRPM7 channels, which is significant for cell signaling and ion channel regulation in pharmacological research (Holderby & Kozak, 2024).
- Investigating the influence of solvent type and pH on protein adsorption onto silica surface by evanescent-wave cavity ring-down spectroscopy.: This study uses TRIS Hydrochloride to explore protein-silica interactions, providing insights into surface chemistry and biomolecular adsorption processes (Alnaanah & Mendes, 2024).
Other Notes
The pH values of all buffers are temperature and concentration dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany
Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 9310-500GM | 04055977229226 |
| 9350-5KG | 04055977229233 |
| 9380-25KG | 04055977229240 |