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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IHC, WB
Citations:
13
biological source
sheep
Quality Level
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, rat
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... TPM3(7170)
Immunogen
Epitope: 5NM1 and 5NM2
Synthetic peptide corresponding to the 9d exon from the gamma gene of tropomyosin.
Application
Detect Tropomyosin using this Anti-Tropomyosin Antibody, 5NM1 & 5NM2 validated for use in WB, IC, IH.
Research Category
Metabolism
Metabolism
Research Sub Category
Muscle Physiology
Muscle Physiology
Western Blot: 1:100-1:500. Antibody reacts with a band at 29-30kDa.
Immunocytochemistry: 1:100-1:500
Immunohistochemistry: 1:100-1:500
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:100-1:500
Immunohistochemistry: 1:100-1:500
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes Tropomyosin 5NM1 and 5NM2.
Physical form
Affinity purified immunoglobulin in PBS (liquid).
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
The molecular composition of neuronal microfilaments is spatially and temporally regulated.
Weinberger, R, et al.
The Journal of Neuroscience, 16, 238-252 (1996)
Functional effects of mutations in the tropomyosin-binding sites of tropomodulin1 and tropomodulin3.
Lewis, RA; Yamashiro, S; Gokhin, DS; Fowler, VM
Cytoskeleton (Hoboken, N.J.) null
Staffan Grenklo et al.
European journal of cell biology, 87(11), 905-920 (2008-09-03)
Tropomyosin is a coiled-coil alpha-helical protein, which self-associates in a head-to-tail fashion along polymers of actin to produce thin filaments. Mammalian non-muscle cells express a large number of tropomyosin isoforms, which are differentially regulated during embryogenesis and associated with specialized
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB5447 | 04053252582332 |