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ABN213

Anti-IL-12 alpha Antibody

Name: Anti-IL-12 alpha Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Synonym(s):

Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35, NK cell stimulatory factor chain 1, NKSF1

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB

Citations:

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

NCBI accession no.

NP_000873

UniProt accession no.

P29459

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... IL12A(3592)

Description

General description

Interleukin-12 alpha (IL-12A) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35), IL-12 subunit p35, or NK cell stimulatory factor chain 1 (NKSF-1). IL-12A is a cytokine that, along with IL12B, forms a disulfide-linked heterodimer interleukin IL-12. IL-12 alpha functions as a regulator of T cell mediated cytotoxicity, interferon-gamma production, lymphocyte proliferation and activation of natural killer cells.

~25 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to the near C-terminus of human IL-12 alpha.

Application

Immunohistochemistry Analysis: A 1:16,000-32,000 dilution from a representative lot detected IL-12 alpha in human tonsil and human brain tissue.

This IL-12 alpha antibody is validated for use in WB & IHC for the detection of the IL-12 alpha protein.

Biochem/physiol Actions

This antibody recognizes the near C-terminus of IL-12 alpha

Analysis Note

Evaluated by Western Blotting in human lymph node tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected IL-12 alpha in 10 µg of human lymph node tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Replaces: MABN1084

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c