Key Documents

View All Documentation

ABN899

Anti-Olig-2 Antibody

Name: Anti-Olig-2 Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Synonym(s):

Oligodendrocyte transcription factor 2, bHLHe19, Olg-2, Oligo2, RACK17, RK17

Select a Size

Change View

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ICC, IHC, IP, WB

Citations:

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat, human

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin), immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

NP_058663

UniProt accession no.

Q9EQW6

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... OLIG2(10215)

Description

General description

Oligodendrocyte transcription factor 2 (UniProt Q9EQW6; also known as bHLHe19, Olg-2, Oligo2, RACK17, RK17) is encoded by the Olig2 (also known as Bhlhb1) gene (Gene ID 50913) in murine species. Olig2 is a basic helix-loop-helix (bHLH) transcription factor expressed in a spinal cord ventricular zone domain where it mediates the sequential generation of motoneurons and oligodendrocytes during embryogenesis. Olig2 also functions as an anti-neurogenic factor in pMN progenitors at early time points to sustain the cycling progenitor pool. The anti-neurogenicity of Olig2 is also responsible for its role in tumorigenesis, especially in brain tumors and leukemia. Due to its expression in glioblastoma and other diffuse gliomas, Olig2 is a useful diagnostic marker of these brain tumors.

~37 kDa observed. 32.40 kDa calculated.

Immunogen

KLH-conjugated linear peptide corresponding to a sequence in the N-terminal region of mouse Olig-2.

Application

Anti-Olig-2 Antibody is an antibody against Olig-2 for use in Western Blotting, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry (Paraffin).

Immunoprecipitation Analysis: 10 µg from a representative lot immunoprecipitated Olig-2 in 500 µg of mouse brain tissue lysate.
Immunohistochemistry Analysis: An 1:500 dilution from a representative lot detected Olig-2 in rat hindbrain tissue sections.
Immunocytochemistry Analysis: An 1:500 dilution from a representative lot detected Olig-2 in PC12 cells.

Physical form

Purified rabbit polyclonal antibody in PBS and 0.1 % sodium azide.

Analysis Note

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Olig-2 in 10 µg of mouse brain tissue lysate.

Other Notes

Concentration: Please refer to lot specific datasheet.

Replaces: AB15328

Still not finding the right product?

Explore all of our products under Anti-Olig-2 Antibody

— or —

Try our Product Selector Tool to narrow your options

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c