MAB1613
Anti-Kinesin Antibody, heavy chain, non-neuronal KHC, clone H1
clone H1, Chemicon®, from mouse
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
H1, monoclonal
Application:
ELISA, ICC, IHC, IP, RIA, WB
Citations:
16
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
H1, monoclonal
species reactivity
rat, human, bovine
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, radioimmunoassay: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... KIF5B(3799)
Immunogen
Epitope: heavy chain, non-neuronal KHC
Application
Anti-Kinesin Antibody, heavy chain, non-neuronal KHC, clone H1 detects level of Kinesin & has been published & validated for use in ELISA, IP, RIA, WB, IC, IH.
Immunohistochemistry on paraformaldehyde fixed tissue. Also works for EM.
Immunocytochemistry: paraformaldehyde fixed cells; 5-10′ RT, freshly made 4% PFA; permeabilize with 0.1-.2% triton X-100 in 3% normal serum blocking buffer
Immunoblotting: recognizes 124kDa KHC from non-neuronal samples.
Immunoprecipitation
Inhibition of kinesin mediated transport
EIA/RIA
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: paraformaldehyde fixed cells; 5-10′ RT, freshly made 4% PFA; permeabilize with 0.1-.2% triton X-100 in 3% normal serum blocking buffer
Immunoblotting: recognizes 124kDa KHC from non-neuronal samples.
Immunoprecipitation
Inhibition of kinesin mediated transport
EIA/RIA
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Reacts with the major form of heavy chain of non-neuronal KHC near the N-terminus.
Physical form
Format: Purified
Liquid in 0.02 M Phosphate buffer, 0.25 M NaCl.pH 7.6 with 0.1% sodium azide.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
12 - Non Combustible Liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic.
Lippincott-Schwartz, J, et al.
The Journal of cell biology, 128, 293-306 (1995)
G Vancoillie et al.
The Journal of investigative dermatology, 114(3), 421-429 (2000-02-26)
Microtubuli play an important role in the organization of organelles and membrane traffic. They are present in melanocytic dendrites through which melanosomes are transported towards keratinocytes. Besides the actin-based motility systems, microtubuli-associated motor proteins also play a critical role in
Wen-Jun Wang et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(1), 62-69 (2013-10-12)
Previous studies identified a family of organic anion transport proteins (OATPs), many of which have C-terminal PDZ binding consensus sequences. In particular, the C-terminal four amino acids of Oatp1a1, a transporter on rat and mouse hepatocytes, comprise a consensus binding
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB1613 | 04053252661358 |