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Merck
CN

MAB19294

Anti-Integrin beta 1 (CD29) Antibody

CHEMICON®, mouse monoclonal, TASC/9D11

Synonym(s):

CD29

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
TASC/9D11, monoclonal
Species reactivity:
chicken
Application:
ICC, IP
Citations:
11
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Product Name

Anti-Integrin β1 Antibody, active β1 integrins, clone TASC/9D11, clone TASC/9D11, Chemicon®, from mouse

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

TASC/9D11, monoclonal

species reactivity

chicken

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, immunoprecipitation (IP): suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGB1(3688)

Immunogen

E10 chick brain glial cells
Epitope: active beta1 integrins

Application

Detect the Integrin β1 protein using this Anti-Integrin β1, active β1 integrins, clone TASC/9D11 validated for use in IP & ICC.
Western blot: Not effective

Immunocytochemistry

Immunoprecipitation

Biological activity: Functionally inhibits attachment to vitronectin. Activates attachment to other substrates.



Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reactive with the extracellular domain of chicken integrin beta 1

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.02M PB +0.25 M NaCl, pH=7.6 with 0.1% Sodium Azide.

Preparation Note

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vitronectin and thrombospondin promote retinal neurite outgrowth: developmental regulation and role of integrins.
Neugebauer, K M, et al.
Neuron, 6, 345-358 (1991)
L R Strachan et al.
Experimental cell research, 314(3), 441-452 (2007-11-27)
Cell migration is essential for proper development of numerous structures derived from embryonic neural crest cells (NCCs). Although recent work has shown that receptor recycling plays an important role in NCC motility on laminin, the molecular mechanisms regulating NCC motility
Cell-surface regulation of beta 1-integrin activity on developing retinal neurons.
Neugebauer, K M and Reichardt, L F
Nature, 350, 68-71 (1991)



Global Trade Item Number

SKUGTIN
MAB1929404053252319006