MAB1945
Anti-Vitronectin Antibody, clone BV2
clone BV2, Chemicon®, from mouse
Synonym(s):
Serum spreading factor, S-protein
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
BV2, monoclonal
Application:
ELISA, FACS, IHC, IP, WB
Citations:
44
Quality Level
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
BV2, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, flow cytometry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... VTN(7448)
Immunogen
Purified human plasma vitronectin (Preissner, 1985).
Application
Anti-Vitronectin Antibody, clone BV2 is an antibody against Vitronectin for use in ELISA, FC, IP, WB, IH.
ELISA
Immunoprecipitation
Western blot
Immunohistochemistry/immunofluorescence
Inhibits endothelial cell adhesion and spreading on vitronectin-coated surfaces.
Flow Cytometry
Optimal working dilutions must be determined by the end user.
Immunoprecipitation
Western blot
Immunohistochemistry/immunofluorescence
Inhibits endothelial cell adhesion and spreading on vitronectin-coated surfaces.
Flow Cytometry
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
ECM Proteins
Biochem/physiol Actions
Human vitronectin. Specificity determined by ELISA and immunoprecipitation of I125 labeled vitronectin purified from plasma (Zanetti et al., 1994). The antibody reacts with vitronectin both in its native and denatured form.
Physical form
Format: Purified
Purified immunoglobulin by Protein A chromatography. Liquid in PBS containing 0.05% sodium azide and 0.1% BSA.
Preparation Note
Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
Clustering of vitronectin and RGD peptides on microspheres leads to engagement of integrins on the luminal aspect of endothelial cell membrane
Zanetti, A. et al.
Blood, 84, 1116-1123 (1994)
Complement activation and inflammatory processes in Drusen formation and age related macular degeneration.
L V Johnson, W P Leitner, M K Staples, D H Anderson
Experimental Eye Research null
R J Falk et al.
The American journal of pathology, 127(1), 182-190 (1987-04-01)
The S protein (S) binds to the attack complex of complement (C5b-9) in plasma preventing cytolysis. Using immunofluorescence microscopy, the authors determined the distribution of S in human renal tissue and its relationship to C5b-9, immunoglobulins, C3, albumin, and fibronectin.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB1945 | 04053252317453 |