MAB2052
Anti-Disialoganglioside GD2 Antibody, clone 14G2a
clone 14.2Ga, Chemicon®, from mouse
Synonym(s):
Anti-GD2 Antibody, Clone 14G2a Anti-GD2, GD2 Detection Antibody
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
14.2Ga, monoclonal
Species reactivity:
human
Application:
FACS, IF, IHC
Citations:
8
biological source
mouse
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
14.2Ga, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable
isotype
IgG2a
shipped in
wet ice
target post-translational modification
unmodified
Application
Immunohistochemistry (frozen tissue sections)(Cheresh et al., 1986)
Immunofluorescence of cells in culture
Flow cytometry: 1-2 μg per 10E6 cells
Cytotoxicity for GD2 positive cells (Mujoo et al., 1987, 1989)
Optimal working dilutions must be determined by end user.
Immunofluorescence of cells in culture
Flow cytometry: 1-2 μg per 10E6 cells
Cytotoxicity for GD2 positive cells (Mujoo et al., 1987, 1989)
Optimal working dilutions must be determined by end user.
Anti-Disialoganglioside GD2 Antibody, clone 14G2a detects level of Disialoganglioside GD2 & has been published & validated for use in FC, IF, IH.
Biochem/physiol Actions
Reacts specifically with human GD2 ganglioside.
Physical form
Cell culture supernatant in 0.02M PB, pH 7.6, 0.25M NaCl containing 0.1% Sodium Azide
Format: Purified
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis.
Cheresh, D A, et al.
Cancer Research, 46, 5112-5118 (1986)
Patrizia Garbati et al.
Biomedicines, 8(11) (2020-11-07)
To overcome the lack of effective pharmacological treatments for high-risk neuroblastoma (HR-NB), the development of novel in vitro and in vivo models that better recapitulate the disease is required. Here, we used an in vitro multiclonal cell model encompassing NB
Functional properties and effect on growth suppression of human neuroblastoma tumors by isotype switch variants of monoclonal antiganglioside GD2 antibody 14.18.
Mujoo, K, et al.
Cancer Research, 49, 2857-2861 (1989)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB2052 | 04053252615207 |