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Merck
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MAB2251

Anti-Integrin β1 Antibody, clone B3B11

clone B3B11, Chemicon®, from mouse

Synonym(s):

CD29

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
B3B11, monoclonal
Species reactivity:
human
Application:
FACS, IHC, IP, WB
Citations:
16
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biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

B3B11, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGB1(3688)

Immunogen

source is Jurkat T-leukemic cell line

Application

Immunoprecipitation

Immunohistochemistry on frozen sections

Flow cytometry

Immunoblotting (Western)

Stimulates adhesion of cells to extracellular matrix proteins1

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins
Anti-Integrin β1 Antibody, clone B3B11 is an antibody against Integrin β1 for use in FC, IP, WB, FUNC, IH.

Biochem/physiol Actions

Reacts with the human integrin beta1 subunit. Specificity verified by preclearing of beta1in immunoprecipitation, flow cytometry on transfectant cells displaying human beta1 integrin, and reactivity with purified beta1. Epitope lies within the same cluster recognized by MAB2250, and within amino acids 648-670 of the mature beta1 integrin chain.1

Physical form

Format: Purified
Purified immunoglobulin from Protein A Sepharose chromatography. Liquid in 0.02M PB pH 7.6, 0.25M NaCl containing 0.1% sodium azide.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Sepharose is a trademark of Cytiva

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sarah L Londrigan et al.
Journal of virology, 77(17), 9486-9501 (2003-08-14)
Rotaviruses utilize integrins during virus-cell interactions that lead to infection. Cell binding and infection by simian rotavirus SA11 were inhibited by antibodies (Abs) to the inserted (I) domain of the alpha2 integrin subunit. To determine directly which integrins or other
Interactions between collagen IV and collagen-binding integrins in renal cell repair after sublethal injury.
Nony, P A and Schnellmann, R G
Molecular Pharmacology, 60, 1226-1234 (2001)
Enhanced peritoneal ovarian tumor dissemination by tissue transglutaminase.
Satpathy, M; Cao, L; Pincheira, R; Emerson, R; Bigsby, R; Nakshatri, H; Matei, D
Cancer Research null



Global Trade Item Number

SKUGTIN
MAB225104053252357862