Merck
CN
All Photos(1)

Documents

Safety Information

11074440001

Roche

Penicillin-Streptomycin

suitable for cell culture, lyophilized (clear, colorless solution after reconstitution), non-sterile; 0.2 μm filtered, sufficient for 20 mL

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
antibiotic

sterility

non-sterile; 0.2 μm filtered

Quality Level

100

form

lyophilized (clear, colorless solution after reconstitution)

usage

sufficient for 20 mL

manufacturer/tradename

Roche

concentration

50 mg/mL streptomycin in 0.9% NaCl (as sulfate)
50,000 U/mL penicillin in 0.9% NaCl

technique(s)

cell culture | mammalian: suitable

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell wall synthesis | interferes
protein synthesis | interferes

storage temp.

2-8°C

Related Categories

General description

Cytotoxic concentration: 10,000 IU/ml penicillin, 20 mg/ml streptomycin
Penicillin (Penicillin G) inhibits bacterial growth by inhibiting peptidoglycan synthesis. Streptomycin belongs to the family of aminoglycoside antibiotics, and inhibits bacterial growth by inhibiting protein synthesis. Penicillin-Streptomycin is used for the prevention and elimination of bacterial contaminants in cell culture.
Penicillin (Penicillin G) inhibits bacterial growth by inhibiting peptidoglycan synthesis. Streptomycin belongs to the family of aminoglycoside antibiotics and inhibits bacterial growth by inhibiting protein synthesis.
Penicillin G, sodium salt; streptomycin sulfate
Sensitive organisms:
  • Gram-positive bacteria (penicillin)
  • Gram-negative bacteria (streptomycin)
  • Stability:Penicillin: 3 days
  • Streptomycin: 3 days in media at +37 °C

Application

Penicillin-Streptomycin has been used for the prevention and elimination of bacterial contaminants in cell culture.

Physical form

Lyophilizate, 50,000 U/ml penicillin G and 50 mg/ml streptomycin (as sulfate) in 0.9% NaCl

Preparation Note

Working concentration: 100 IU/ml penicillin
100 μg/ml streptomycin

Reconstitution

Dissolve in 20mL distilled water.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Disease relevant modifications of the methylome and transcriptome by particulate matter (PM2.5) from biomass combustion
He?elbach K, et al.
Epigenetics, 1-14 (2017)
Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma
Hooijkaas A, et al.
Oncoimmunology, 1(5), 609-617 (2012)
Lysozyme and penicillin inhibit the growth of anaerobic ammonium-oxidizing planctomycetes.
Hu Z, et al.
Applied and Environmental Microbiology, 79(24), 7763-7769 (2013)
Krishnan MohanKumar et al.
American journal of physiology. Gastrointestinal and liver physiology, 318(4), G705-G716 (2020-02-25)
Anemia is a frequent diagnosis in critically ill infants, but the clinical implications of severe anemia in these patients remain unclear. In this study, we examined preweaned mice to investigate the effects of severe anemia during early infancy on gut
Irene Iscla et al.
Nature communications, 5, 4891-4891 (2014-09-11)
The antibiotic streptomycin is widely used in the treatment of microbial infections. The primary mechanism of action is inhibition of translation by binding to the ribosome, but how it enters the bacterial cell is unclear. Early in the study of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service