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Merck
CN

03762

2,6-Di-tert-butyl-4-methylphenol

tested according to Ph. Eur.

Synonym(s):

Butylhydroxytoluenum, 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, Butylhydroxytoluene, DBPC

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About This Item

Linear Formula:
[(CH3)3C]2C6H2(CH3)OH
CAS Number:
Molecular Weight:
220.35
UNSPSC Code:
12352300
NACRES:
NA.21
PubChem Substance ID:
EC Number:
204-881-4
Beilstein/REAXYS Number:
1911640
MDL number:
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agency

tested according to Ph. Eur.

Quality Level

vapor density

7.6 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

autoignition temp.

878 °F

bp

265 °C (lit.)

mp

69-73 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

InChI key

NLZUEZXRPGMBCV-UHFFFAOYSA-N

Gene Information

human ... CAPN1(823)
rat ... Capn1(29153), Nos1(24598)

Application


  • Quantitative analysis of residual butylated hydroxytoluene and butylated hydroxyanisole in Salmo salar, milk, and butter by liquid chromatography-tandem mass spectrometry.: This study provides a quantitative analysis of residual 2,6-Di-tert-butyl-4-methylphenol (BHT) and butylated hydroxyanisole (BHA) in various food products. The research highlights the presence and concentration of these antioxidants in fish, milk, and butter, demonstrating their widespread use in food preservation (Galal et al., 2024).

  • The key factors of solid nanodispersion for promoting the bioactivity of abamectin.: This research investigates the use of BHT in solid nanodispersions to enhance the bioactivity of abamectin, a widely used insecticide. The study identifies key factors that improve the stability and effectiveness of the formulation, suggesting applications in agricultural biotechnology (Ding et al., 2024).



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pictograms

Environment

signalword

Warning

hcodes

Storage Class

11 - Combustible Solids

flash_point_f

260.6 °F - open cup

flash_point_c

127 °C - open cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Hazard Classifications

Aquatic Chronic 1



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I Björkhem et al.
Arteriosclerosis and thrombosis : a journal of vascular biology, 11(1), 15-22 (1991-01-01)
Rabbits fed a 1% cholesterol diet with or without the antioxidant butylated hydroxytoluene (BHT) developed typical atherosclerotic lesions. The addition of BHT gave higher levels of total cholesterol (+40%), triglycerides (+250%), low density lipoprotein (LDL), and very low density lipoprotein
Li Li et al.
Circulation, 105(7), 861-867 (2002-02-21)
Current epidemiological data suggest that dental infections affecting tooth-supporting tissues (periodontitis) can disseminate into the systemic circulation and thereby contribute to atherosclerosis progression. To test this hypothesis, we investigated the effect of repeated systemic inoculations with Porphyromonas gingivalis (Pg), a
A M Vijesh et al.
European journal of medicinal chemistry, 46(11), 5591-5597 (2011-10-05)
In the present study two new series of Hantzsch 1,4-dihydropyridine derivatives (1,4-DHPs) containing substituted pyrazole moiety (4a-f and 5a-f) were synthesized by the reaction of 3-aryl-1H-pyrazole-4-carbaldehydes with 1,3-dicarbonylcompounds (ethylacetoacetate and methylacetoacetate) and ammonium acetate. The newly synthesized compounds were characterized



Global Trade Item Number

SKUGTIN
03762-500G04061838627841
03762-5KG04061833458464