12806
O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
≥97.0% (N), solid, for peptide synthesis
Synonym(s):
N,N,N′,N′-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate, TBTU
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About This Item
Linear Formula:
C11H16N5O · BF4
CAS Number:
Molecular Weight:
321.08
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
7066325
Product Name
O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate, ≥97.0% (N)
Quality Level
assay
≥97.0% (N)
form
solid
mp
205 °C (dec.) (lit.)
solubility
acetonitrile: 0.1 g/mL, clear, colorless
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
F[B-](F)(F)F.CN(C)\C(On1nnc2ccccc12)=[N+](/C)C
InChI
1S/C11H16N5O.BF4/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1
InChI key
JKEKMBGUVUKMQB-UHFFFAOYSA-N
Application
Coupling reagent which is ideally suited for solid-phase peptide synthesis.
Other Notes
Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound; Coupling reagent which is ideally suited for solid-phase peptide synthesis.
signalword
Danger
hcodes
Hazard Classifications
Flam. Sol. 1 - Skin Sens. 1A
Storage Class
4.1A - Other explosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Samer Al-Gharabli et al.
Materials (Basel, Switzerland), 11(5) (2018-05-08)
Advanced ceramic materials with a well-defined nano-architecture of their surfaces were formed by applying a two-step procedure. Firstly, a primary amine was docked on the ordered nanotubular ceramic surface via a silanization process. Subsequently, single-wall carbon nanotubes (SWCNTs) were covalently
S. Zimmer et al. et al.
Proc. 22nd Eur. Pept. Symp.: Peptides 1992 null
Parvin Zakeri-Milani et al.
EXCLI journal, 16, 650-662 (2017-07-12)
Gemcitabine (Gem) is used as a single agent or in combination with other anticancer agents to treat many types of solid tumors. However, it has many limitations such as a short plasma half-life, dose-limiting toxicities and drug resistance. Cell-penetrating peptides
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 12806-250G-F | 04061832747422 |
| 12806-100G-F | 04061832747415 |
| 12806-1KG-F | 04061826189917 |
| 12806-25G-F | 04061838725363 |
| 12806-5G-F | 04061838725370 |