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Merck
CN

141194

Ponceau S

Dye content 75 %

Synonym(s):

3-Hydroxy-4-(2-sulfo-4-[4-sulfophenylazo]phenylazo)-2,7-naphthalenedisulfonic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C22H12N4Na4O13S4
CAS Number:
Molecular Weight:
760.57
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
228-319-2
Colour Index Number:
27195
MDL number:
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form

powder

Quality Level

composition

Dye content, 75%

technique(s)

microbe id | staining: suitable

λmax

352 nm, 520 nm (2nd)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].[Na+].[Na+].Oc1c(\N=N\c2ccc(cc2S([O-])(=O)=O)\N=N\c3ccc(cc3)S([O-])(=O)=O)c4ccc(cc4cc1S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C22H16N4O13S4.4Na/c27-22-20(43(37,38)39)10-12-9-16(41(31,32)33)6-7-17(12)21(22)26-25-18-8-3-14(11-19(18)42(34,35)36)24-23-13-1-4-15(5-2-13)40(28,29)30;;;;/h1-11,27H,(H,28,29,30)(H,31,32,33)(H,34,35,36)(H,37,38,39);;;;/q;4*+1/p-4/b24-23+,26-25+;;;;

InChI key

KQHKSGRIBYJYFX-WNDMICSESA-J

General description

Ponceau S (C.l. 27195) is an anionic, very hydrophilic disazo dye. It is also known as fast ponceau 2B.

Application

Ponceau S is widely used to stain proteins on gel electropherograms. It is a suitable stain for proteins adsorbed onto nitrocellulose membranes. It also has applications in botanical staining manuals as a stain for sieve plate elements.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signaling.
Carraway KL III
The Journal of Biological Chemistry, 274(9), 5263-5266 (1999)
Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose.
Aebersold RH
Proceedings of the National Academy of Sciences of the USA, 84(20), 6970-6974 (1987)
Expression of cyclooxygenase-2 (COX-2) in human invasive transitional cell carcinoma (TCC) of the urinary bladder.
Mohammed SI
Cancer Research, 59(22), 5647-5650 (1999)



Global Trade Item Number

SKUGTIN
141194-100G04061838733955
141194-25G04061838733962