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Merck
CN

33247

Urea

ACS reagent grade, ≥99%, solid, puriss. p.a., reag. Ph. Eur.

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:
NH2CONH2
CAS Number:
Molecular Weight:
60.06
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-315-5
MDL number:
Beilstein/REAXYS Number:
635724
Assay:
≥99%, 99-101% (calc. on dry substance)
Form:
solid
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Product Name

Urea, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99%

Quality Level

agency

reag. Ph. Eur.

grade

ACS reagent, puriss. p.a.

assay

≥99%, 99-101% (calc. on dry substance)

form

solid

impurities

alkalic reac. substances, complies, ≤0.0005% heavy metals (as Pb), ≤0.05% ammonium (NH4), ≤0.1% biuret

ign. residue

≤0.01% (as SO4)

loss

≤1.0% loss on drying, 105°C, 1 h

mp

132-135 °C

solubility

H2O: soluble 480 g/L at 20 °C

density

1.335 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤5 mg/kg, sulfate (SO42-): ≤10 mg/kg

cation traces

Fe: ≤2 mg/kg

suitability

in accordance for appearance of solution, in accordance for identity

functional group

amine

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

General description

Urea is a colorless, odorless solid. It has prism-like crystals. It forms insoluble nitrate salts with nitric acid and oxalate salts with oxalic acid. On reaction with alkanes or substituted alkanes, it affords crystal-lattice inclusion compounds.
Urea is the most commonly used slow release nitrogen fertilizer.

Application

Urea has been used in the following studies:
  • Synthesis of SnO2 nanoparticles.
  • Synthesis of urethanes, ureides and semicarbazides.
  • Denaturation of protein isolated from Saccharomyces cerevisiae Y15696 strain.
  • Protein electrophoretic studies.
Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.


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wgk

WGK 1

flash_point_f

Not applicable

Storage Class

11 - Combustible Solids

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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