81275
Poly(ethylene glycol)
tested according to Ph. Eur., 20,000
Synonym(s):
Macrogol 20,000, Polyethylene glycol, Polyoxyethylene, PEG
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About This Item
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12161900
MDL number:
agency
tested according to Ph. Eur.
Quality Level
form
flakes
mol wt
16000-24000
greener alternative product characteristics
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
application(s)
pharmaceutical (small molecule)
greener alternative category
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
General description
Polyethylene glycol (PEG) is a versatile and non-ionic polymer commonly used in a range of industrial and pharmaceutical applications due to its low toxicity, hydrophobic nature, and semicrystalline structure. It is made up of CH2-CH2O repeating units and its ability to exist in both monomer and aqueous phases at high temperatures makes it valuable for a range of research applications.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.
Application
- Novel fibrous Ag(NP) decorated clay-polymer composite: Implications in water purification contaminated with predominant micro-pollutants and bacteria: This study demonstrates the use of poly(ethylene glycol) (PEG) for the creation of novel fibrous clay-polymer composites, enhancing the removal efficiency of micro-pollutants and bacteria in water treatment systems (Goswami et al., 2024).
- Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol: This review addresses the advances in the uniform production of poly(ethylene glycol) (PEG), critical for its application in drug delivery and pharmaceutical formulations, discussing the material′s solubility, biocompatibility, and stabilization properties (Bento et al., 2024).
- Assessing the structural stability and drug encapsulation efficiency of poly(ethylene glycol)-poly(L-lactic acid) nanoparticles loaded with atorvastatin calcium: The study evaluates the use of PEG in polymeric nanoparticles, focusing on optimizing drug encapsulation efficiency and stability, which is pivotal for effective drug delivery systems (Feng et al., 2024).
- Design and Evaluation of Nanoscale Materials with Programmed Responsivity towards Epigenetic Enzymes: This research explores the role of PEG in designing responsive nanoscale materials aimed at targeting epigenetic enzymes, showcasing PEG′s versatility in enhancing pharmaceutical applications (Ray et al., 2024).
- Membranes composed of poly(lactic acid)/poly(ethylene glycol) and Ora-pro-nóbis (Pereskia aculeata Miller) extract for dressing applications: This article highlights the application of PEG in developing biocompatible and efficient wound dressing materials, combining poly(lactic acid) and natural extracts to enhance healing processes (Mendes et al., 2024).
Biochem/physiol Actions
Polyethylene glycols (PEGs) or macrogols are broadly used as additives in cosmetics and pharmaceuticals. Addition of this hydrophilic polymer blocks and reverses some types of surfactant inactivation in vitro. PEG can be used as a macroinitiator, stabilizer, or dispersant in the field of emulsion polymerization with the help of its derivatives or modifications.
Features and Benefits
- Environment friendly
- Biocompatible
- Unique solvent solution
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
281.5 °F - closed cup
flash_point_c
138.6 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
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Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 81275-1KG | 04061826715369 |