Key Documents

View All Documentation

E1769

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride

Name: <I>N</I>-(3-Dimethylaminopropyl)-<I>N</I>′-ethylcarbodiimide hydrochloride
Brand: SIAL

BioXtra

Synonym(s):

N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride, EDAC, EDC, EDC hydrochloride, WSC hydrochloride

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₈H₁₇N₃ · HCl

CAS Number:

25952-53-8

Molecular Weight:

191.70

NACRES:

NA.25

PubChem Substance ID:

24894433

UNSPSC Code:

12161700

EC Number:

247-361-2

MDL number:

MFCD00012503

Beilstein/REAXYS Number:

5764110

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride, BioXtra

product line

BioXtra

Quality Level

200

form

powder

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

mp

110-115 °C (lit.)

solubility

H₂O: 0.5 M, clear to very slightly hazy, colorless to very faintly yellow

anion traces

sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

storage temp.

−20°C

SMILES string

Cl.CCN=C=NCCCN(C)C

InChI

1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H

InChI key

FPQQSJJWHUJYPU-UHFFFAOYSA-N

Description

Application

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride has been used:

for post-fixation and crosslinking of small ribonucleic acid (RNAs) species from formalin fixed paraffin embedded (FFPE) tissues, for fluorescent in situ hybridisation (FISH) and immunofluorescence (IF) signals
for cross-linking of nanofiber matrices with mouse lung extract
for activation of substrate XNA oligonucleotides

Biochem/physiol Actions

Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided.

Still not finding the right product?

Explore all of our products under N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride

pictograms

GHS06,GHS08,GHS09

signalword

Danger

target_organs

Stomach,large intestine,lymph node

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

hcodes

H302,H311,H315,H317,H319,H373,H410

pcodes

P273 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338 - P314

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

用于细胞膜片组织工程的基于聚N-异丙基丙烯酰胺的智能表面

组织工程已成为治疗受损或患病的器官和组织（例如血管和尿囊）的关键治疗工具。

Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

A cell sorter with modified bamboo charcoal for the efficient selection of specific antibody-producing hybridomas.

Chien-Chen Lin et al.

Biomaterials, 31(32), 8445-8453 (2010-08-17)

Monoclonal antibodies (mAbs) have been proven useful in research and clinical applications. However, the generation of mAbs by conventional hybridoma technology is time-, cost- and labor-consuming. Here we developed a simplified procedure for efficient generation and selection of antibody-producing hybridomas

Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers

Taylor AI and Holliger P

Nature Protocols, 10(10), 1625-1625 (2015)

Organ-derived coatings on electrospun nanofibers as ex vivo microenvironments

Fischer SN, et al.

Biomaterials, 32(2), 538-546 (2011)

View All Related Papers

Global Trade Item Number

SKU	GTIN
E1769-5G	04061833602218
E1769-10G	04061833602188
E1769-1G	04061833602195
E1769-25G	04061833602201

Key Documents

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride

BioXtra

Select a Size

About This Item

Product Name

product line

Quality Level

form

impurities

ign. residue

mp

solubility

anion traces

cation traces

storage temp.

SMILES string

InChI

InChI key

Application

Biochem/physiol Actions

Still not finding the right product?

Safety Information

pictograms

signalword

target_organs

Storage Class

flash_point_f

flash_point_c

ppe

hcodes

pcodes

Hazard Classifications

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Protocols and Articles

Articles

Peer Reviewed Papers

Global Trade Item Number