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G0400007

Glycerol mono-oleate

Name: Glycerol mono-oleate
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₄₀O₄

CAS Number:

25496-72-4

Molecular Weight:

356.54

MDL number:

MFCD00042735

UNSPSC Code:

41116107

NACRES:

NA.24

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Properties

grade

pharmaceutical primary standard

API family

glyceryl monooleate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O(CC(O)CO)C(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-

InChI key

RZRNAYUHWVFMIP-KTKRTIGZSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glycerol mono-oleate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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High-throughput discovery of novel steric stabilizers for cubic lyotropic liquid crystal nanoparticle dispersions.

Josephine Y T Chong et al.

Langmuir : the ACS journal of surfaces and colloids, 28(25), 9223-9232 (2012-05-29)

High-throughput methodologies have been employed to establish structure-property relationships and assess the effectiveness of nonionic steric stabilizers for inverse bicontinuous cubic lyotropic liquid crystalline nanoparticulate dispersions of monoolein and phytantriol. The ability of the stabilizers to disperse the lipids was

Lipid crystallization: from self-assembly to hierarchical and biological ordering.

Chandrashekhar V Kulkarni

Nanoscale, 4(19), 5779-5791 (2012-08-18)

Lipid crystallization is ubiquitous in nature, observed in biological structures as well as in commercial products and applications. In a dehydrated state most of the lipids form well ordered crystals, whereas in an aqueous environment they self-assemble into various crystalline

Distinct solubility and cytotoxicity regimes of paclitaxel-loaded cationic liposomes at low and high drug content revealed by kinetic phase behavior and cancer cell viability studies.

Victoria M Steffes et al.

Biomaterials, 145, 242-255 (2017-09-11)

Lipid-based particles are used worldwide in clinical trials as carriers of hydrophobic paclitaxel (PTXL) for cancer chemotherapy, albeit with little improvement over the standard-of-care. Improving efficacy requires an understanding of intramembrane interactions between PTXL and lipids to enhance PTXL solubilization

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Global Trade Item Number

SKU	GTIN
G0400007	04061833800751