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G5767

Sigma-Aldrich

D-(+)-Glucose

ACS reagent

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Synonym(s):
Dextrose
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
50-99-7
Molecular Weight:
180.16
Beilstein:
1724615
EC Number:
200-075-1
MDL number:
MFCD00063774
PubChem Substance ID:
24895228
NACRES:
NA.21

biological source

wheat

Quality Level

200

grade

ACS reagent

form

powder

optical activity

[α]25/D +52.5 to +53.0°(lit.)

impurities

Starch, passes test
≤0.002 meq/g Titratable acid
≤0.005% Insoluble matter

ign. residue

≤0.02%

loss

≤0.2% loss on drying, 105°C

color

colorless

mp

150-152 °C (lit.)

anion traces

chloride (Cl-): ≤0.01%
sulfate, sulfite (as SO42-): ≤0.005%

cation traces

Fe: ≤5 ppm
heavy metals (as Pb): ≤5 ppm

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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General description

D-glucose, an aldohexose, possesses four chiral carbon atoms. It is an important product obtained from starch hydrolyzed by acid and/or enzymes.

Application

D-(+)-Glucose has been used:
  • as a supplement in Dulbecco′s phosphate-buffered saline (DPBS) for standardized serum bactericidal assay (SBA) using human complement
  • as a component in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES)-buffered Tyrode′s solution to treat the excised diaphragmatic specimens to assess the effect of osmolarity changes on the intrinsic lymphatic pumping mechanism
  • to study the effect of restoring circulating glucose content in insulin-responsive neurons of rats
  • for oral glucose tolerance tests (OGTTs)

Biochem/physiol Actions

Glucose, the universal energy source for all human cells, is the vital precursor for the production and conversion of several downstream carbohydrates. The uptake of glucose is a key indicator of cellular energy metabolism. Glucose infusion can block the release of oxytocin and vasopressin by insulin-induced hypoglycemia in humans.

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2 g + 15mL.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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