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Merck
CN

I0627

Isobarbituric acid

analytical standard

Synonym(s):

2,4,5-Trihydroxypyrimidine, 5-Hydroxyuracil

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About This Item

Empirical Formula (Hill Notation):
C4H4N2O3
CAS Number:
Molecular Weight:
128.09
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-829-9
Beilstein/REAXYS Number:
127205
MDL number:
Technical Service
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grade

analytical standard

Quality Level

assay

~98%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

>300 °C (dec.) (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

O=C1CNC(=O)NC1=O

InChI

1S/C4H4N2O3/c7-2-1-5-4(9)6-3(2)8/h1H2,(H2,5,6,8,9)

InChI key

FQXOOGHQVPKHPG-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Gunn A Hildrestrand et al.
Experimental cell research, 315(15), 2558-2567 (2009-05-30)
Adipose-tissue derived mesenchymal stem cells (AT-MSCs) are a promising tool for use in cell-based therapies. However, in vitro expansion is required to obtain clinically relevant cell numbers, and this might increase the chance of genomic instability. DNA repair is crucial
Grégory Eot-Houllier et al.
Nucleic acids research, 35(10), 3355-3366 (2007-05-01)
Evidence has emerged that repair of clustered DNA lesions may be compromised, possibly leading to the formation of double-strand breaks (DSB) and, thus, to deleterious events. The first repair event occurring at a multiply damaged site (MDS) is of major
Zuzanna Bukowy et al.
Nucleic acids research, 36(15), 4975-4987 (2008-07-29)
Werner syndrome (WS) is a premature aging disorder caused by mutations in the WS gene (WRN). Although WRN has been suggested to play an important role in DNA metabolic pathways, such as recombination, replication and repair, its precise role still



Global Trade Item Number

SKUGTIN
I0627-1G04061826691342