Skip to Content
Merck
CN

Key Documents

View All Documentation

PHR1673

Lidocaine Related Compound H

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

N-(2,6-Dimethylphenyl)chloroacetamide, n-(2,6-Dimethylphenyl)chloroacetamide, 1-Chloroacetylamino-2,6-dimethylbenzene, 2-Chloro-2′,6′-acetoxylidide, 2-Chloro-2′,6′-dimethylacetanilide, 2-Chloro-N-(2,6-dimethylphenyl)acetamide, N-(2,6-Dimethylphenyl)-2-chloroacetamide, N-(2,6-Xylyl)chloroacetamide, N-Chloroacetyl-2,6-dimethylaniline, Chloroacetamido-2,6-xylidine

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
ClCH2CONHC6H3(CH3)2
CAS Number:
1131-01-7
Molecular Weight:
197.66
NACRES:
NA.24
PubChem Substance ID:
329823547
UNSPSC Code:
41116107
EC Number:
214-460-7
MDL number:
MFCD00000926
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1366080

API family

lidocaine

CofA

current certificate can be downloaded

packaging

pkg of 100 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

150-151 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Cc1cccc(C)c1NC(=O)CCl

InChI

1S/C10H12ClNO/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6H2,1-2H3,(H,12,13)

InChI key

FPQQSNUTBWFFLB-UHFFFAOYSA-N

General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Lidocaine Related Compound H is one of the impurities of the local anesthetic lidocaine found in bulk powder and dosage forms.

Application

This pharmaceutical secondary standard can also be used as follows:

  • Simultaneous estimation of lidocaine hydrochloride, tribenoside, and their related compounds in pharmaceutical formulations by high-performance liquid chromatography (HPLC) combined with a UV/Vis detector
  • Multi-analysis of dexpanthenol, lidocaine hydrochloride, mepyramine maleate, and their related impurities in their combined dosage forms by high-performance liquid chromatography (HPLC)-diode array detection
  • Development of an HPLC method for the estimation of three active pharmaceutical ingredients along with their impurities in a semi-solid topical formulation

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2078 in the slot below. This is an example certificate only and may not be the lot that you receive.

Still not finding the right product?

Explore all of our products under Lidocaine Related Compound H

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKUGTIN
PHR1673-100MG04061834801573