Key Documents

View All Documentation

PHR2068

Efavirenz Related Compound A

Name: Efavirenz Related Compound A
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol, (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₃H₁₁ClF₃NO

CAS Number:

209414-27-7

Molecular Weight:

289.68

UNSPSC Code:

41116107

NACRES:

NA.24

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1234125

CofA

current certificate can be downloaded

packaging

pkg of 50 mg

application(s)

pharmaceutical

format

neat

storage temp.

2-8°C

SMILES string

FC(F)(F)[C@@](O)(c2c(ccc(c2)Cl)N)C#CC1CC1

InChI

1S/C13H11ClF3NO/c14-9-3-4-11(18)10(7-9)12(19,13(15,16)17)6-5-8-1-2-8/h3-4,7-8,19H,1-2,18H2/t12-/m0/s1

InChI key

KEMUGFRERPPUHB-LBPRGKRZSA-N

Description

General description

Efavirenz USP Related Compound A is an impurity of the non-nucleoside HIV-1 reverse transcriptase inhibitor, efavirenz. Efavirenz is an antiretroviral medication used to treat and prevent Type-1 HIV.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Efavirenz USP Related Compound A may be used as a reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB8450 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Still not finding the right product?

Explore all of our products under Efavirenz Related Compound A

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Efavirenz

USP42/NF37: United States Pharmacopeia and National Formulary

United States Pharmacopeia, 36(3), 1554-1554 (2019)

Development and validation of a reverse-phase HPLC method for analysis of efavirenz and its related substances in the drug substance and in a capsule formulation

Montgomery ER, et al.

Journal of Pharmaceutical and Biomedical Analysis, 25(2), 267-284 (2001)

Global Trade Item Number

SKU	GTIN
PHR2068-50MG	04061835234820