215112
Phosphorous acid
99%
Synonym(s):
Phosphonic acid
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About This Item
Empirical Formula (Hill Notation):
H3O3P
CAS Number:
Molecular Weight:
82.00
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
237-066-7
MDL number:
Assay:
99%
Form:
crystals or chunks, flakes
Quality Level
assay
99%
form
crystals or chunks, flakes
pH
(acidic)
solubility
water: soluble
density
1.651 g/mL at 25 °C (lit.)
SMILES string
[H]P(O)(O)=O
InChI
1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3)
InChI key
ABLZXFCXXLZCGV-UHFFFAOYSA-N
General description
Phosphorous acid (or phosphonic acid) is a phosphorus oxoacid commonly used as an intermediate in chemical synthesis for the production of various phosphorus compounds. It is also used as a strong reducing agent in organic synthesis.
Application
Phosphorous acid (H3PO3, orthophosphorous acid) may be used as one of the reaction components for the synthesis of the following:
- α-aminomethylphosphonic acids via Mannich-Type Multicomponent Reaction
- 1-aminoalkanephosphonic acids via amidoalkylation followed by hydrolysis
- N-protected α-aminophosphonic acids (phospho-isosteres of natural amino acids) via amidoalkylation reaction
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
危险化学品
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Amidoalkylation of phosphorous acid.
Vinyukov AV, et al.
Russ. J. Gen. Chem., 85(2), 366-369 (2015)
Review on modern advances of chemical methods for the introduction of a phosphonic acid group.
Charles S Demmer et al.
Chemical reviews, 111(12), 7981-8006 (2011-10-21)
Marco Esposito et al.
European journal of oral implantology, 6(3), 227-236 (2013-11-02)
To evaluate the safety and clinical efficacy of a novel surface treatment (SurfLink®, Nano Bridging Molecules, Gland, Switzerland) on titanium dental implants. SurfLink consists of a monolayer of permanently bound multi-phosphonic acid molecules, which mimics the surface of naturally occurring
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 215112-100G | 04061838773395 |
| 215112-500G | 04061837759970 |
| 215112-2KG | 04061838773401 |
| 215112-4X2KG | 04061838773418 |