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Merck
CN

A1010

Arsenic(III) oxide

ReagentPlus®, ≥99.0%

Synonym(s):

Arsenic trioxide, Arsenous acid

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About This Item

Empirical Formula (Hill Notation):
As2O3
CAS Number:
Molecular Weight:
197.84
NACRES:
NA.55
PubChem Substance ID:
UNSPSC Code:
12171602
EC Number:
215-481-4
MDL number:
Assay:
≥99.0%
Form:
powder
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vapor pressure

0 hPa ( 66 °C)

Quality Level

product line

ReagentPlus®

assay

≥99.0%

form

powder

storage temp.

room temp

SMILES string

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChI key

IKWTVSLWAPBBKU-UHFFFAOYSA-N

General description

Arsenic(III) oxide, also known as arsenic trioxide, is an amphoteric oxide that serves as a raw material for the synthesis of several arsenic-based compounds. It is utilized to decolorize glasses and enamels. Its efficacy in treating in acute promyelocytic leukaemia (APL) has been investigated.

Application

Arsenic(III) oxide was used in a study detailing the effect of arsenic trioxide in combination with γ-irradiation to elucidate the hemoglobin (Hb).

Biochem/physiol Actions

Very potent agent against acute promyelocytic leukemia (APL). Causes skin, lung and bladder cancer.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany


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Danger

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

target_organs

Respiratory system,Cardio-vascular system,Gastrointestinal tract

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

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Related Content

Product Information Sheet


Combined effect of arsenic trioxide and radiation on physical properties of hemoglobin biopolymer.
Saad-El-Din AA, et al.
Journal of Radiation Research and Applied Sciences, 7(2), 411-416 (2014)
E Lengfelder et al.
Leukemia, 26(3), 433-442 (2011-09-10)
Arsenic trioxide (ATO) is presently the most active single agent in the treatment of acute promyelocytic leukemia (APL). This review provides insights into the mode of action and the pharmacological properties of ATO, and summarizes the most relevant results of
Dikshith TSS
Handbook of Chemicals and Safety, 92-92 (1992)



Global Trade Item Number

SKUGTIN
A1010-100G04061835277025
A1010-1KG04061826272169
A1010-250G04061835277032
A1010-25G04061835277049