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Merck
CN

108M-9

CD8 (C8/144B) Mouse Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
C8/144B, monoclonal
Application:
IHC (p)
Citations:
5
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

diluted ascites fluid

antibody product type

primary antibodies

clone

C8/144B, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (108M-94), vial of 0.5 mL concentrate (108M-95), bottle of 1.0 mL predilute (108M-97), vial of 1.0 mL concentrate (108M-96), bottle of 7.0 mL predilute (108M-98)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG1κ

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... CD8A(925)

General description

Anti-CD8 is a T cell marker for the detection of cytotoxic/suppresser cells of blood lymphocytes. CD8 is also detected on NK cells, most thymocytes, a subpopulation of null cells and bone marrow cells. This antibody, along with other markers, can be used to distinguish between reactive and neoplastic T-cells.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

CD8 Positive Control Slides, Product No. 108S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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Regulatory Information

监管及禁止进口产品

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Immunohistological analysis of human lymphoma: correlation of histological and immunological categories.
H Stein et al.
Advances in cancer research, 42, 67-147 (1984-01-01)
F Phan-Dinh-Tuy et al.
Molecular immunology, 19(12), 1649-1654 (1982-12-01)
Three human lymphocyte differentiation antigens, specific of the entire T-cell population, of the helper/inducer T-cell subset, and of the cytotoxic/suppressor T-cell subset have been identified, using mouse monoclonal antibodies obtained from Dr. P. Kung. Various T-cell populations were radio-labelled, the
M L Rossi et al.
Journal of clinical pathology, 41(3), 314-319 (1988-03-01)
Twenty four meningiomas (17 benign and seven "atypical" were reacted with a panel of monoclonal antibodies to macrophages, lymphocytes, and HLA DR antigens. All the tumours contained macrophages but these cells were more numerous in the atypical meningiomas. Lymphocytes, almost



Global Trade Item Number

SKUGTIN
108M-960841683123309
108M-940841683123286
108M-950841683123293
108M-96-RUO04061836538774
108M-970841683123316
108M-980841683123323