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Merck
CN

134M-1

CD34 (QBEnd/10) Mouse Monoclonal Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
QBEnd/10, monoclonal
Application:
IHC (p)
Citations:
4
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

QBEnd/10, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (134M-14), vial of 0.5 mL concentrate (134M-15), bottle of 1.0 mL predilute (134M-17), vial of 1.0 mL concentrate (134M-16), bottle of 7.0 mL predilute (134M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG1

control

placenta, tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... CD34(947)

General description

CD34 is a cell surface glycophosphoprotein expressed on human hematopoietic progenitor cells and can be used for identifying blast cells. CD34 is a marker for vascular endothelial cells and has been shown in the literature to be highly sensitive to angiosarcomas and Kaposi’s sarcomas. In addition, CD34 is expressed in soft tissue tumors such as gastrointestinal stromal tumors (GIST).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
CD34 Positive Control Slides, Product No. 134S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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Regulatory Information

监管及禁止进口产品

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Articles

结直肠癌是男性和女性中第三大常见癌症。预计2016年将发生136,000例结直肠癌。

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.


Joanna Kiśluk et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 22(1), 33-39 (2013-03-08)
Gastrointestinal stromal tumors (GISTs) are the most common cancers of mesenchymal origin in the abdomen. An approximately 95% of GISTs show positive expression of the membrane receptor c-kit (CD117 antigen), which currently constitutes the basis for histopathological diagnosis if this
E A Sankey et al.
The Journal of pathology, 161(3), 267-271 (1990-07-01)
Kaposi's sarcomas are seen more commonly in routine histopathology laboratories since the advent of the more widespread and aggressive variant of the disease associated with HIV infection. Distinguishing nodular lesions from other spindle cell and vascular tumours can sometimes be
Goran Torlakovic et al.
Archives of pathology & laboratory medicine, 126(7), 823-828 (2002-06-29)
The immunohistochemical detection of CD34 protein using QBEND10 antibody in bone marrow trephine biopsies was shown recently to be a precise method for quantitation of blasts and a possibly useful approach in diagnosis and classification of myelodysplastic syndrome. To evaluate



Global Trade Item Number

SKUGTIN
134M-140841683124610
134M-16-RUO04061836539351
134M-180841683124658
134M-150841683124627
134M-160841683124634
134M-170841683124641