156M-8
CD56 (123C3.D5) Mouse Monoclonal Antibody
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
123C3.D5, monoclonal
Application:
IHC (p)
Citations:
10
biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
123C3.D5, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (156M-84), vial of 0.5 mL concentrate (156M-85), bottle of 1.0 mL predilute (156M-87), vial of 1.0 mL concentrate (156M-86), bottle of 7.0 mL predilute (156M-88)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1κ
control
neuroblastoma
shipped in
wet ice
storage temp.
2-8°C
visualization
membranous
Gene Information
human ... NCAM1(4684)
General description
Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived cell lines, tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Other Notes
CD56 Positive Control Slides, Product No. 156S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Regulatory Information
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R Gerardy-Schahn et al.
International journal of cancer. Supplement = Journal international du cancer. Supplement, 8, 38-42 (1994-01-01)
Monoclonal antibodies (MAbs) ranked together as small-cell-lung-cancer (SCLC) Cluster I MAbs are directed against the neural cell adhesion molecule NCAM (CD 56) and have been shown to be useful reagents in SCLC diagnosis and therapy. We analyzed the epitopes recognized
C E Moolenaar et al.
Cancer research, 50(4), 1102-1106 (1990-02-15)
Monoclonal antibodies (MAbs) 123C3 and 123A8 generated against a membrane preparation of a small cell lung carcinoma (SCLC) specimen recognize not only SCLC and bronchial carcinoids but also a significant portion of non-small cell lung carcinomas (non-SCLC) of various histological
R E Kibbelaar et al.
European journal of cancer (Oxford, England : 1990), 27(4), 431-435 (1991-01-01)
We investigated the expression of the neural cell adhesion molecule (NCAM) in a series of surgically resected lung carcinomas of various histological subtypes by means of a panel of monoclonal antibodies recognising different N-CAM epitopes. In a subgroup of 56
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 156M-86-RUO | 04061836539726 |
| 156M-87 | 0841683125129 |
| 156M-84 | 0841683125099 |
| 156M-85 | 0841683125105 |
| 156M-86 | 0841683125112 |
| 156M-88 | 0841683125136 |