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24368C

EX-CELL® Advanced CHO Feed 1 (without glucose)

Synonym(s):

EX-CELL® Advanced CHO Feed 1

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About This Item

NACRES:
NA.71
UNSPSC Code:
12352200
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Product Name

EX-CELL® Advanced, CHO Feed 1 (without glucose). Use 34.10 g/L. See information sheet, 24368C @ www.sigmaaldrich.com for hydration instructions

Quality Level

500

product line

EX-CELL®

form

dry powder

technique(s)

cell culture | mammalian: suitable (suspension)

shipped in

ambient

storage temp.

2-8°C

General description

EX-CELL® Advanced CHO Feed 1 (without glucose) is chemically-defined and contains no animal derived components. This feed is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Fed-batch Medium (14366C or 24366C). This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME).

Preparation Note

Formulated to contain 34.1 grams of powder per liter of medium.

Other Notes

Submit the EX-CELL Advanced CHO Fed-batch request form to get in touch with a SAFC representative.

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

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CorrosionExclamation mark
GHS05,GHS07

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Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

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Articles

EX-CELL® Advanced™ CHO Fed-Batch System – Bioprocessing Technology Institute, Singapore Case Study

In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.

Low-Impurity Iron Sources: Case Studies in EX-CELL® Advanced Medium

Discover how low-impurity iron sources improve reliability and performance in recombinant protein production with EX-CELL® Advanced medium.

One-step Feed Optimization for Upstream Cell Culture Processes

Optimizing feed for upstream cell culture improves monoclonal antibody production, but requires balancing outcomes for both viable cell density and productivity.

View All Articles

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EX-CELL Advanced CHO Feed 1
Pao-Chun Lin et al.
mAbs, 11(5), 965-976 (2019-05-03)
Chinese hamster ovary (CHO) cells are the biopharmaceutical industry's primary means of manufacturing therapeutic proteins, including monoclonal antibodies. The major challenge in cell line development for the production of recombinant biopharmaceuticals lies in generating and isolating rare high-producing stable clones

Global Trade Item Number

SKUGTIN
24368C-25K04061834411567
24368C-50L04061838821829
24368C-10L04061838822031
24368C-1L04061838822048
24368C-50K04061834411574