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Merck
CN

51085

Isobutyryl-L-carnitine

≥97.0% (TLC)

Synonym(s):

(2R)-3-Carboxy-N,N,N-trimethyl-2-(2-methyl-1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine isobutyryl ester, iC4-Carnitine

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About This Item

Empirical Formula (Hill Notation):
C11H21NO4
CAS Number:
Molecular Weight:
231.29
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Beilstein/REAXYS Number:
4138517
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Product Name

Isobutyryl-L-carnitine, ≥97.0% (HPLC)

Quality Level

assay

≥97.0% (HPLC)

form

powder

optical activity

[α]/D -22±2°, c = 1 in H2O

impurities

≤10% water

color

white

storage temp.

2-8°C

SMILES string

C[N+](C)(C)C[C@H](OC(C(C)C)=O)CC([O-])=O

InChI

1S/C11H21NO4/c1-8(2)11(15)16-9(6-10(13)14)7-12(3,4)5/h8-9H,6-7H2,1-5H3/t9-/m1/s1

InChI key

LRCNOZRCYBNMEP-SECBINFHSA-N

Biochem/physiol Actions

Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases (ACADs), which are a group of mitochondrial enzymes involved in the metabolism of fatty acids or branched-chain amino acids.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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M Fontaine et al.
Clinica chimica acta; international journal of clinical chemistry, 273(2), 161-170 (1998-07-10)
Here we report on a patient with severe ("non-classic") carnitine palmitoyltransferase type II (CPT II) deficiency. Hypoglycemia prompted by an infectious episode and associated with non-ketotic dicarboxylic aciduria orientated diagnosis towards beta-oxidation deficiency disorders. Blood carnitine levels revealed a secondary
D P Shalev et al.
Andrologia, 18(4), 368-375 (1986-07-01)
When washed human sperm were incubated in a modified Krebs-Ringer buffer solution in the absence of exogenous metabolizable substrates at 30 degrees C they maintained progressive motility for at least six hours. Under these conditions the spermatozoa apparently utilize endogenous
K Matsumoto et al.
Clinica chimica acta; international journal of clinical chemistry, 216(1-2), 135-143 (1993-07-16)
An immobilized enzyme reactor, made up acylcarnitine hydrolase, carnitine dehydrogenase and diaphorase in sequence, was developed for the sensitive and selective determination of urinary free and individual acylcarnitines by a reversed-phase high-performance liquid chromatography. A 100-microliter urine sample was directly



Global Trade Item Number

SKUGTIN
51085-10MG04061832419435
51085-50MG04061832419442