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69602

4-Methylumbelliferyl-β-D-glucuronide hydrate

β-glucuronidase substrate, fluorogenic, ≥99.0% (HPLC), powder or crystals, suitable for fluorescence

Synonym(s):

4-Methylumbelliferyl-β-D-glucopyranosiduronic acid, MUG

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About This Item

Empirical Formula (Hill Notation):
C16H16O9 · xH2O
CAS Number:
881005-91-0
Molecular Weight:
352.29 (anhydrous basis)
NACRES:
NA.32
PubChem Substance ID:
57652201
UNSPSC Code:
12352204
EC Number:
228-186-0
MDL number:
MFCD09039280
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Product Name

4-Methylumbelliferyl-β-D-glucuronide hydrate, suitable for fluorescence, ≥99.0% (HPLC)

Quality Level

100

assay

≥99.0% (HPLC)

form

powder or crystals

impurities

≤0.1% free 4-Methylumbelliferone, ≤15% water

solubility

DMSO: 50 mg/mL, clear, colorless to very faintly yellow

fluorescence

λex 365 nm; λem 445 nm in 0.1 M phosphate pH 6.5

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

O.CC1=CC(=O)Oc2cc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)ccc12

InChI

1S/C16H16O9.H2O/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22;/h2-5,11-14,16,18-20H,1H3,(H,21,22);1H2/t11-,12-,13+,14-,16+;/m0./s1

InChI key

URVSQZMOFUEQAW-YYHOVTOASA-N

General description

4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) is a fluorogenic substrate.

Application

4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) has been used:
  • as a β-glucuronidase (GUS) substrate for fluorimetric analysis of reporter gene expression in Arabidopsis thaliana
  • for the fluorimetric assay for GUS activity
  • to measure liposome lysis by n-octylglucoside

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF9585
BCCB1971
BCBQ3280V
BCBQ1430V
BCBX3960

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R.B. Thompson et al.
Analytical Letters, 18, 1847-1847 (1985)
Zeng Tao et al.
Nature plants, 5(4), 424-435 (2019-04-10)
Some overwintering plants acquire competence to flower, after experiencing prolonged cold in winter, through a process termed vernalization. In the crucifer plant Arabidopsis thaliana, prolonged cold induces chromatin-mediated silencing of the potent floral repressor FLOWERING LOCUS C (FLC) by Polycomb
Jean-Félix Dallery et al.
Journal of experimental botany, 71(10), 2910-2921 (2020-02-02)
Infection of Arabidopsis thaliana by the ascomycete fungus Colletotrichum higginsianum is characterized by an early symptomless biotrophic phase followed by a destructive necrotrophic phase. The fungal genome contains 77 secondary metabolism-related biosynthetic gene clusters, whose expression during the infection process

Global Trade Item Number

SKUGTIN
69602-1G04061832785301
69602-250MG04061832785318