75447
2-Oxoadipic acid
≥95.0% (HPLC)
Synonym(s):
α-Ketoadipic acid, 2-Oxoadipate, 2-Oxohexanedioic acid
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About This Item
Empirical Formula (Hill Notation):
C6H8O5
CAS Number:
Molecular Weight:
160.12
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Assay:
≥95.0% (HPLC), ≥97.0% (T)
Form:
powder
Quality Level
assay
≥95.0% (HPLC), ≥97.0% (T)
form
powder
lipid type
saturated FAs
storage temp.
2-8°C
SMILES string
OC(=O)CCCC(=O)C(O)=O
InChI
1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)
InChI key
FGSBNBBHOZHUBO-UHFFFAOYSA-N
Application
- Engineering of phenylalanine dehydrogenase from Thermoactinomyces intermedius for the production of a novel homoglutamate: Showcases the application of 2-oxoadipic acid in enzyme engineering, enhancing biocatalytic processes for the production of novel compounds, vital for pharmaceutical and chemical industries (Tariq et al., 2022).
Biochem/physiol Actions
Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metabolite transporters.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
Natalia S Nemeria et al.
Biochimica et biophysica acta. Bioenergetics, 1859(9), 932-939 (2018-05-13)
Herein are reported findings in vitro suggesting both functional and regulatory cross-talk between the human 2-oxoglutarate dehydrogenase complex (hOGDHc), a key regulatory enzyme within the tricarboxylic acid cycle (TCA cycle), and a novel 2-oxoadipate dehydrogenase complex (hOADHc) from the final
Nikolaus Sonnenschein et al.
BMC systems biology, 6, 41-41 (2012-05-16)
Integrating gene expression profiles and metabolic pathways under different experimental conditions is essential for understanding the coherence of these two layers of cellular organization. The network character of metabolic systems can be instrumental in developing concepts of agreement between expression
D Darmaun et al.
Journal of chromatography, 620(1), 33-38 (1993-10-22)
A method is described for measuring glutamine (GLN) and alpha-ketoglutarate (KG) concentration and specific activity (SA) using high-performance liquid chromatography (HPLC). Plasma GLN and KG are separated on miniature ion-exchange columns. KG is derivatized with O-phenylene diamine, the derivative is
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 75447-100MG | 04061832907970 |
| 75447-500MG | 04061832907987 |