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Merck
CN

90998

1,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt

≥98.0% (TLC)

Synonym(s):

1,2-Ditetradecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt, L-α-Phosphatidyl-DL-glycerol, dimyristoyl, L-α-Phosphatidyl-DL-glycerol, dimyristoyl sodium salt, DMPG, DMPG-Na, PG(14:0/14:0), Tetradecanoic acid 1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester monosodium salt

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About This Item

Linear Formula:
C34H66O10PNa
CAS Number:
Molecular Weight:
688.85
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
51191904
MDL number:
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biological source

synthetic

Quality Level

assay

≥98.0% (TLC)

form

powder

functional group

ester

lipid type

phosphoglycerides

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C34H67O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-33(37)41-29-32(30-43-45(39,40)42-28-31(36)27-35)44-34(38)26-24-22-20-18-16-14-12-10-8-6-4-2;/h31-32,35-36H,3-30H2,1-2H3,(H,39,40);/q;+1/p-1/t31?,32-;/m1./s1

InChI key

QLNOOKSBAYIHQI-SKZICHJRSA-M

Application

Prototype for the preparation of liposomes with negatively charged hydrophilic head groups. Phase transitions, close-packing ratios, and ion permeability are all strongly affected by the presence of a stoichiometric amount (1:2) of divalent cations.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Matthew G K Benesch et al.
Biochimica et biophysica acta, 1848(11 Pt A), 2878-2888 (2015-08-16)
The thermotropic phase behavior and organization of model membranes composed of binary mixtures of the quadruple-chained, nominally dianionic phospholipid tetramyristoylcardiolipin (TMCL) with the double-chained, monoanionic phospholipid dimyristoylphosphatidylglycerol (DMPG) were examined by differential scanning calorimetry (DSC) and Fourier-transform infrared (FTIR) spectroscopy.
Zoltan Beck et al.
Vaccine, 33(42), 5578-5587 (2015-09-16)
Liposomes have shown promise as constituents of adjuvant formulations in vaccines to parasitic and viral diseases. A particular type of liposomal construct, referred to as Army Liposome Formulation (ALF), containing neutral and anionic saturated phospholipids, cholesterol, and monophosphoryl lipid A
Nicolas Bertram et al.
Langmuir : the ACS journal of surfaces and colloids, 31(30), 8386-8391 (2015-07-15)
Nanodisc films are a promising approach to study the equilibrium conformation of membrane bound proteins in native-like environment. Here we compare nanodisc formation for NADPH-dependent cytochrome P450 oxidoreductase (POR) using two different scaffold proteins, MSP1D1 and MSP1E3D1. Despite the increased



Global Trade Item Number

SKUGTIN
90998-100MG04061833253526
90998-1G04061826656099