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A0972

Apolipoprotein A-II from human plasma

Name: Apolipoprotein A-II from human plasma
Brand: SIGMA

≥95% (SDS-PAGE), buffered aqueous solution

Synonym(s):

Apo A-II

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About This Item

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD00132612

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Properties

biological source

human plasma

Quality Level

200

assay

≥95% (SDS-PAGE)

form

buffered aqueous solution

mol wt

17.38 kDa

UniProt accession no.

P02652

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... APOA2(336)

Description

General description

Forms dimers in aqueous solutions with an association constant of 5 × 10⁴M^-1. The association is accompanied by an enhancement of ~35% in α-helical content.

Application

Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).

Biochem/physiol Actions

Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.

Physical form

Solution in 10 mM ammonium bicarbonate.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

高风险级别生物产品--人源产品

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Articles

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Cholesterol Transport

Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.