A5139
Asp-Phe methyl ester
≥98%
Synonym(s):
N-(L-α-Aspartyl)-L-phenylalanine methyl ester, Asp-Phe-OMe, Aspartame
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About This Item
Linear Formula:
HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
CAS Number:
Molecular Weight:
294.30
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352108
EC Number:
245-261-3
MDL number:
Beilstein/REAXYS Number:
2223850
Product Name
Asp-Phe methyl ester, ≥98%
Quality Level
assay
≥98%
form
powder
sweetness
160-200 × sucrose
color
white to off-white
storage temp.
2-8°C
SMILES string
COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O
InChI
1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChI key
IAOZJIPTCAWIRG-QWRGUYRKSA-N
General description
Asp-Phe methyl ester (aspartame, APM, ASP), a dipeptide ester, is made up of phenyl alanine and aspartic acid. Its genotoxic effects have been investigated. Its interaction with certain hydrocolloids has been studied.
Application
Asp-Phe methyl ester is used for the preparation of Ad libitum Standard Chow, with ad libitum drinking water (animals control diet) containing Asp-Phe methyl ester. It is also used for the TFA diet preparation (TFA diet with ad lib drinking water contains Asp-Phe methyl ester.
Biochem/physiol Actions
Asp-Phe methyl ester (Asp-Phe-OMe) is used as a synthetic sweeter, sugar substitute. Asp-Phe methyl ester is being studied for a variety of potential benefits as a nutrition supplement, such as the delay of osteoarthritis and modulation of rheumatoid factor activity. Asp-Phe methyl ester is being studied for its effect on thrombin activity and blood clotting.
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Aspartame: in perspective.
Caseley J and Dixon W.
Nutrition & Food Science, 31(1), 23-27 (2001)
Genotoxicity of aspartame.
Rencuzogullari E, et al.
Drug and Chemical Toxicology, 27(3), 257-268 (2004)
Interaction of aspartame with selected hydrocolloids: solubility of aspartame.
Wafwoyo W, et al.
Food Hydrocolloids, 13(4), 299-302 (1999)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A5139-1G | 04061833375440 |
| A5139-25G | 04061833375457 |
| A5139-5G | 04061833375464 |