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Sigma-Aldrich

Antifoam 204

mixture of organic polyether dispersions

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Synonym(s):
organic antifoam
MDL number:
NACRES:
NA.25

form

liquid

technique(s)

microbiological culture: suitable

viscosity

400 cP(lit.)

density

1.01 g/cm3 at 25 °C (lit.)

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General description

Antifoam function as an effective foam suppressor. Antifoam 204 contains 100% active components and is a mixture of organic non-silicone polypropylene-based polyether dispersions. It does not contain mineral oil. Antifoam 204 can itself be considered a surfactant, but it contains no other surfactants. This product is synthetic and not derived from animal or plant sources. Antifoam 204 can be sterilized repeatedly. The flow properties of Antifoam 204 are such that it can be pumped to a fermenter on an as-needed basis. For use in microbiological media, Sigma recommends a starting concentration of between 0.005% and 0.01%.

Application

Antifoam 204 has been used:

  • to suppress bubbling in thylakoid solutions during intramembrane isoprene quantification
  • as a component of fed-batch continuous culture fermentation medium
  • to suppress severe foaming in fermenter

Other Notes

Contains 100% active components and is a mixture of non-silicone organic defoamers in a polyol dispersion. Can be sterilized repeatedly.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Physiology of Aspergillus niger in oxygen-limited continuous cultures: Influence of aeration, carbon source concentration and dilution rate
Diano A, et al.
Biotechnology and Bioengineering, 103(5), 956-965 (2009)
Ultrasound-assisted fermentation enhances bioethanol productivity
Sulaiman AZ, et al.
Biochemical Engineering Journal, 54(3), 141-150 (2011)
A novel noncovalent complex of chorismate mutase and DAHP synthase from Mycobacterium tuberculosis: protein purification, crystallization and X-ray diffraction analysis
M Okvist, et al.
Acta Crystallographica Section F, Structural Biology and Crystallization Communications, 65(10), 1048-1052 (2009)
Concentration of isoprene in artificial and thylakoid membranes
Harvey CM, et al.
Journal of Bioenergetics and Biomembranes, 47(5), 419-429 (2015)
Erin E Johnson et al.
Bioresource technology, 209, 1-7 (2016-03-08)
Waste crude glycerol from biodiesel production can be used to produce biobutanol using Clostridium pasteurianum with the main products being n-butanol, 1,3-propanediol (PDO) and ethanol. There has been much discrepancy and mystery around the cause and effect of process parameters

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