Skip to Content
Merck
CN

Key Documents

View All Documentation

A6677

Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro

synthetic (organicorganic), ≥97% (HPLC), fibronectin binding inhibitor, powder

Synonym(s):

Arginyl-Glycyl-Asparagyl-Serinyl-Prolyl-Alaninyl-Serinyl-Serinyl-Lysyl-Proline, RGDSPASSKP

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C40H68N14O16
CAS Number:
91575-25-6
Molecular Weight:
1001.05
UNSPSC Code:
12352202
PubChem Substance ID:
24891126
NACRES:
NA.77
MDL number:
MFCD00076453
Form:
powder
Assay:
≥97% (HPLC)
Biological source:
synthetic (organic
organic)
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro, ≥97% (HPLC)

biological source

synthetic (organic
organic)

Quality Level

200

assay

≥97% (HPLC)

form

powder

UniProt accession no.

P02751

storage temp.

−20°C

SMILES string

CC(NC(=O)C1CCCN1C(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)CCCNC(N)=N)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)N2CCCC2C(O)=O

InChI

1S/C40H68N14O16/c1-20(31(61)50-24(17-55)35(65)51-25(18-56)34(64)49-22(8-2-3-11-41)37(67)54-14-6-10-28(54)39(69)70)47-36(66)27-9-5-13-53(27)38(68)26(19-57)52-33(63)23(15-30(59)60)48-29(58)16-46-32(62)21(42)7-4-12-45-40(43)44/h20-28,55-57H,2-19,41-42H2,1H3,(H,46,62)(H,47,66)(H,48,58)(H,49,64)(H,50,61)(H,51,65)(H,52,63)(H,59,60)(H,69,70)(H4,43,44,45)

InChI key

JMBLPSUDFRAOLU-UHFFFAOYSA-N

Gene Information

human ... FN1(2335)

Application

Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro has been used to test its effect on the adhesion of Hemophilus somnus in bovine brain endothelial cells.

Biochem/physiol Actions

Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro peptide comprises the RGD sequence and blocks β2-integrin-binding sites.
Inhibits fibronectin binding to fibroblasts.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLBX6470
SLBW4392
SLBV7345
SLBN5891V
SLBM7201V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

E Behling-Kelly et al.
Infection and immunity, 74(9), 5311-5318 (2006-08-24)
Haemophilus somnus can cause a devastating fibrinopurulent meningitis with thrombotic vasculitis and encephalitis in cattle. The mechanisms used by H. somnus to migrate from the bloodstream into the central nervous system (CNS) are unknown. In this study, we demonstrate that
K M Yamada et al.
The Journal of cell biology, 99(1 Pt 1), 29-36 (1984-07-01)
Fibronectin and certain polypeptide regions of this adhesive glycoprotein mediate cell attachment and spreading on various substrates. We explored the theoretical prediction that this adhesive protein could become a competitive inhibitor of fibronectin-mediated processes if present in solution at appropriately
Caterina Cristallini et al.
Journal of applied biomaterials & functional materials, 14(2), e129-e136 (2016-04-09)
The accumulation of amyloid beta protein in the brain causes the cognitive impairment observed in neurodegenerative pathologies such as Alzheimer's disease. The present study aimed to test the hypothesis that a rapid removal of amyloid beta protein peptides from the
View All Related Papers

Global Trade Item Number

SKUGTIN
A6677-1MG04061826731710