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A8960

Sigma-Aldrich

L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate

≥95%

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Synonym(s):
L-Ascorbic acid 2-(dihydrogen phosphate) magnesium salt
Empirical Formula (Hill Notation):
C6H6Mg1.5O9P · xH2O
CAS Number:
1713265-25-8
Molecular Weight:
289.54 (anhydrous basis)
PubChem Substance ID:
329771023
NACRES:
NA.79

biological source

synthetic (organic)

Assay

≥95%

form

powder

technique(s)

HPLC: suitable

color

white to off-white

SMILES string

O=C1O[C@@]([C@@H](O)CO)([H])C([O-])=C1OP([O-])([O-])=O.O=C2O[C@@]([C@@H](O)CO)([H])C([O-])=C2OP([O-])([O-])=O.O.[Mg+2].[Mg+2].[Mg+2]

InChI

1S/2C6H9O9P.3Mg.H2O/c2*7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13;;;;/h2*2,4,7-9H,1H2,(H2,11,12,13);;;;1H2/q;;3*+2;/p-6/t2*2-,4+;;;;/m00..../s1

InChI key

HKRNHMZODRSAPN-IXNKEUJHSA-H

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Application

L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate has been used in mesenchymal stem cells (MSC) expansion medium to incubate scaffolds, in Dulbecco′s modified eagle medium (DMEM) for culturing human umbilical cord cells and mesenchymal stem cells.

Biochem/physiol Actions

L-Ascorbic acid 2-phosphate (AA2P) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays. L-Ascorbic acid 2-phosphate may be used in cell differentiation and tissue engineering applications. Asc-2P is used in studies of gene repression, such as the repression of dihydrotestosterone-induced dickkopf-1 expression.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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25G
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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

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  3. The formula has "XH2O".  How much water is there in my lot of Product A8960, L-Ascorbic acid 2-phospate?

    Because the water content varies from lot to lot, water content is reported on the lot-specific Certificate of Analysis.  Water content is typically in the range of 5 - 7 moles water per mole of ascorbic acid-2-phosphate.

  4. How can I make and keep a solution of Product A8960, L-Ascorbic acid 2-phospate?

    A8960 is soluble in water at 50 mg/ml, forming a clear colorless to yellow solution.  Stocks solutions that are stored at 5 °C are approximately 80% active after 4 weeks.

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Recent studies suggested that dihydrotestosterone (DHT)-driven alteration in the autocrine and paracrine factors may be a key to androgen-potentiated balding. Also, we recently claimed that DHT-inducible dickkopf-1 (DKK-1) is one of the key factors involved in the androgen-potentiated balding. Here
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An enzyme electrode was prepared with acid phosphatase (ACP) for development of a new electric power generation system using ascorbic acid 2-phosphate (AA2P) as a fuel. The properties of the electrode were investigated with respect to biocatalytic dephosphorylation of AA2P
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