A9165
N-Acetyl-L-cysteine
BioReagent, suitable for cell culture
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product line
BioReagent
Assay
≥99% (TLC)
form
powder
technique(s)
cell culture | mammalian: suitable
color
white to off-white
mp
106-108 °C (lit.)
solubility
H2O: 100 mg/mL (with heating)
storage temp.
2-8°C
SMILES string
CC(=O)N[C@@H](CS)C(O)=O
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChI key
PWKSKIMOESPYIA-BYPYZUCNSA-N
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Related Categories
Application
Biochem/physiol Actions
Application
also commonly purchased with this product
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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How to Find a Lot/Batch Number for COA
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Aldrich Products
For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').
For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').
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Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
My media turned yellow when I added N-acetyl cysteine (NAC), Product A9165. Why?
The pH of a 1% solution is 2.0-2.8. You may need to adjust the pH of the media with NaOH. Or, prior to addition to the media, you can initially dilute the NAC with PBS, and then add it to the culture media.
How stable is a solution of Product A9165, N-acetyl cysteine (NAC)?
Aqueous solutions of cysteine oxidize to cystine on contact with air at neutral or alkaline pH. We recommend making aqueous solutions fresh. NAC is relatively stable in acid. Solutions in acid are stable and can be stored at -20 °C.
What concentration of Product A9165, N-Acetyl-L-cysteine (NAC), should I use for cell culture?
Cell culture testing is performed at 0.82 g/L. The exact concentration will depend upon your application.
What is the half life of Product A9165, N-Acetyl-L-cysteine (NAC), in cell culture?
We have not tested the half-life of NAC solutions in our labs here at Sigma. However, this subject has been reviewed in Neuropsychopharmacology, 29, 2018-2023 (2004).
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Articles
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Chromatograms
application for HPLCOur team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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