B169
BRL 37344 sodium salt hydrate
≥98% (HPLC), β3-adrenergic receptor agonist, solid
Synonym(s):
(±)-(R*,R*)-[4-[2-[[2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetic acid sodium hydrate, BRL 37344A
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About This Item
Empirical Formula (Hill Notation):
C19H21ClNNaO4 · xH2O
CAS Number:
Molecular Weight:
385.82 (anhydrous basis)
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Product Name
BRL 37344 sodium salt hydrate, solid
assay
≥98% (HPLC)
Quality Level
form
solid
color
white
solubility
DMSO: 18 mg/mL, clear (warmed)
SMILES string
O.[Na+].C[C@H](Cc1ccc(OCC([O-])=O)cc1)NC[C@H](O)c2cccc(Cl)c2
InChI
1S/C19H22ClNO4.Na.H2O/c1-13(21-11-18(22)15-3-2-4-16(20)10-15)9-14-5-7-17(8-6-14)25-12-19(23)24;;/h2-8,10,13,18,21-22H,9,11-12H2,1H3,(H,23,24);;1H2/q;+1;/p-1/t13-,18+;;/m1../s1
InChI key
YTPAKDODIXRQTF-BNTHFPBMSA-M
Gene Information
human ... ADRB3(155)
Biochem/physiol Actions
BRL 37344 is a selective β3-adrenoceptor agonist.
BRL 37344 is a selective β3-adrenoceptor agonist. Studies support the hypothesis that there are peripheral β3 adrenergic receptors that can reduce food intake and that central β2 or β3 adrenergic receptors mediate the peripheral effects of the β3 agonist.
Features and Benefits
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Disclaimer
Hygroscopic; store desiccated.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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