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Merck
CN

C3011

Cesium chloride

Grade I, ≥99.0%

Synonym(s):

Caesium monochloride, Cesium chloride

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About This Item

Linear Formula:
CsCl
CAS Number:
Molecular Weight:
168.36
NACRES:
NA.75
PubChem Substance ID:
UNSPSC Code:
12352207
EC Number:
231-600-2
MDL number:
Assay:
≥99.0%
Form:
powder
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type

Grade I

Quality Level

assay

≥99.0%

form

powder

mp

645 °C (lit.)

absorption

≤0.2 at 280 in H2O at 50%

application(s)

hematology
histology

SMILES string

[Cl-].[Cs+]

InChI

1S/ClH.Cs/h1H;/q;+1/p-1

InChI key

AIYUHDOJVYHVIT-UHFFFAOYSA-M

Application

Cesium chloride has been used as a component of pipette solution, to record mechanosensitive currents in dorsal root ganglia neurons. It has been used in patch clamping to study neurons in intact myenteric ganglia.
Used for the preparation of electrically conducting glasses.Used to make solutions for the separation of RNA from DNA by density gradient centrifugation.

Biochem/physiol Actions

Oral intake of cesium chloride is known to increase the pH in cancer cells. Mild toxicity of cesium chloride might cause hypotension, gastrointestinal distress, numbness and syncope. It also leads to severe hypokalemia, hypomagnesemia, acute heart attack and polymorphic ventricular tachycardia in episodes.

Analysis Note

Solutions may contain a slight haze.


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pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Patch clamp recording from enteric neurons in situ
Nancy O, et al.
Nature Protocols, 6(1), 15-15 (2011)
Recording of mechanosensitive currents using piezoelectrically driven mechanostimulator
Jizhe H, et al.
Nature Protocols, 6(7), 979-979 (2011)
Petr Melnikov et al.
Biological trace element research, 135(1-3), 1-9 (2009-08-06)
The knowledge about cesium metabolism and toxicity is sparse. Oral intake of cesium chloride has been widely promoted on the basis of the hypothesis referred to as "high pH cancer therapy", a complimentary alternative medicine method for cancer treatment. However



Global Trade Item Number

SKUGTIN
C3011-100G04061833485019
C3011-250G04061833485033
C3011-1KG04061833485026
C3011-25G04061835572212
C3011-500G04061833650639
C3011-50G04061833650646