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D134

3,7-Dimethyl-1-propargylxanthine

Name: 3,7-Dimethyl-1-propargylxanthine
Brand: SIGMA

≥98% (HPLC), powder

Synonym(s):

3,7-Dimethyl-1-(2-propynyl)xanthine, DMPX

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₀N₄O₂

CAS Number:

14114-46-6

Molecular Weight:

218.21

NACRES:

NA.77

PubChem Substance ID:

24277754

UNSPSC Code:

12352200

MDL number:

MFCD00078576

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

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Properties

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

SMILES string

CN1C(=O)N(CC#C)C(=O)c2c1ncn2C

InChI

1S/C10H10N4O2/c1-4-5-14-9(15)7-8(11-6-12(7)2)13(3)10(14)16/h1,6H,5H2,2-3H3

InChI key

IORPOFJLSIHJOG-UHFFFAOYSA-N

Gene Information

human ... ADORA2A(135), ADORA2B(136)
rat ... Adora1(29290), Adora2a(25369)

Description

Application

3,7-Dimethyl-1-propargylxanthine (DMPX) has been used as an A₂ -adenosine receptor (AR) antagonist:

to study its effects on potential modulation of motor output elicited by epidural spinal stimulation (ESS)
to study the role of A_2areceptor in elevating cyclic adenosine monophosphate (cAMP) levels
to study its effects on the cell viability of human gastric cancer cell line

Biochem/physiol Actions

3,7-Dimethyl-1-propargylxanthine (DMPX) is a caffeine analog and A₂-selective adenosine receptor (AR) antagonist.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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