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D3072

Sigma-Aldrich

Doxycycline Hydrochloride, Ready Made Solution

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Synonym(s):
α-6-Deoxy-5-hydroxytetracycline hydrochloride, 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aR,5S,5aR,6R,12aS)-, Doxylin, Idocyklin, Vibramycin hyclate, Vibramycin hydrochloride
Empirical Formula (Hill Notation):
C22H24N2O8 · HCl
CAS Number:
10592-13-9
Molecular Weight:
480.90
MDL number:
MFCD03427564
NACRES:
NA.85

biological source

synthetic

Quality Level

200

sterility

0.22 μm filtered

form

liquid

concentration

100 mg/mL in DMSO

solubility

DMSO: 100 mg/mL

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
mycoplasma
parasites

Mode of action

protein synthesis | interferes

storage temp.

−20°C

InChI

1S/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25-27,31-32H,23H2,1-3H3;1H/b21-13-;/t7-,10+,14+,15-,17-,22-;/m0./s1

InChI key

VLUQVUWDECWBTL-UQVCFKGQSA-N

Related Categories

General description

Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is a Broad spectrum antibiotic and bacteriostatic. Doxycycline shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metalloproteinases) in vivo. Doxycycline is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease acne, rosacea, and rickettsial infections and prophylaxis of anthrax (caused by Bacillus anthracis). It is also effective against Yersinia pestis . Treatment with doxycycline inhibits collagen synthesis.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup

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