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ED4S

Ethylenediaminetetraacetic acid tetrasodium salt hydrate

practical grade, ≥95%

Synonym(s):

EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate hydrate

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About This Item

Linear Formula:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O
CAS Number:
194491-31-1
Molecular Weight:
380.17 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
24894710
EC Number:
200-573-9
Beilstein/REAXYS Number:
3861753
MDL number:
MFCD00150025
UNSPSC Code:
12352116
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grade

practical grade

Quality Level

200

assay

≥95%

form

powder

reaction suitability

reagent type: chelator

solubility

soluble, clear, colorless (32g plus 200ml of water)

InChI

1S/C10H16N2O8.4Na.H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;1H2/q;4*+1;/p-4

InChI key

GXFFSKMBMYHTAE-UHFFFAOYSA-J

Application

EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.
Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.

Preparation Note

Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.

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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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