EMU214881
MISSION® esiRNA
targeting mouse Setd2
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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
GCCCTGAAAAATGACGAGATAATAGATGCCACTCAAAAAGGGAATTGCTCTCGTTTCATGAATCATAGCTGTGAACCAAACTGTGAAACCCAGAAATGGACTGTGAATGGACAGCTGAGGGTTGGATTTTTTACCACCAAACTAGTTCCTTCAGGCTCAGAATTAACTTTTGACTACCAGTTCCAAAGATATGGCAAAGAAGCTCAGAAGTGTTTCTGTGGGTCAGCCAACTGCCGGGGCTACTTGGGAGGAGAAAACAGAGTCAGTATCAGAGCTGCAGGAGGGAAGATGAAAAAGGAACGCTCTCGAAAGAA
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
mouse ... SETD2(235626), Setd2(235626)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Na Liu et al.
Oncology reports, 32(6), 2397-2404 (2014-10-22)
Previously, we reported that hypoxia was able to induce invasion and metastasis in gastric cancer and that hypoxia-inducible factor-1 (HIF-1) is a key factor involved in this tumor type. Krüppel-like factor 8 (KLF8) as a transcriptional repressor has been suggested
Reza K Oqani et al.
Scientific reports, 9(1), 3831-3831 (2019-03-09)
The mRNA processing and export factor, Iws1, interacts with the histone H3/H4 chaperone, Spt6 (Supt6 in mouse gene ontology) and recruits the lysine methyltransferase, Setd2, to chromatin to regulate H3K36me3. This recruitment is known to be crucial for pre-mRNA splicing
Global Trade Item Number
| SKU | GTIN |
|---|---|
| EMU214881-20UG | 04061831392555 |
| EMU214881-50UG | 04061828715602 |