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G2140

L-Glutathione oxidized disodium salt

Name: <SC>L</SC>-Glutathione oxidized disodium salt
Brand: SIGMA

BioReagent, suitable for cell culture

Synonym(s):

GSSG

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₃₀N₆Na₂O₁₂S₂

CAS Number:

103239-24-3

Molecular Weight:

656.59

MDL number:

MFCD00148894

UNSPSC Code:

12352209

PubChem Substance ID:

24895087

NACRES:

NA.75

Beilstein/REAXYS Number:

6265389

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Properties

biological source

yeast

Quality Level

200

product line

BioReagent

assay

≥98%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

ethanol, essentially free

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

storage temp.

−20°C

SMILES string

[Na+].[Na+].N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C([O-])=O)C(=O)NCC(O)=O)C(=O)NCC([O-])=O)C(O)=O

InChI

1S/C20H32N6O12S2.2Na/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38;;/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38);;/q;2*+1/p-2/t9-,10-,11-,12-;;/m0../s1

InChI key

DRFILBXQKYDTFW-JIWRMXRASA-L

Description

Application

For use in cell culture applications as an antioxidant and heavy metal detoxification agent. L-Glutathione oxidized disodium salt has been used in semen processing and evaluation.

Biochem/physiol Actions

Oxidized L-glutathione is frequently measured in vivo as an indicator of oxidative stress.

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

动植物源性产品

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Influence of various antioxidants on microscopic-oxidative stress indicators and fertilizing ability of frozen-thawed bull semen

Sariozkan S, et al.

Acta Veterinaria Brno, 78(3), 463-469 (2009)

Oxidized forms of glutathione in peripheral blood as biomarkers of oxidative stress.

Rossi R

Clinical Chemistry, 52(7), 1406-1414 (2006)

Aldehydic load and aldehyde dehydrogenase 2 profile during the progression of post-myocardial infarction cardiomyopathy: benefits of Alda-1.

Katia M S Gomes et al.

International journal of cardiology, 179, 129-138 (2014-12-03)

We previously demonstrated that reducing cardiac aldehydic load by aldehyde dehydrogenase 2 (ALDH2), a mitochondrial enzyme responsible for metabolizing the major lipid peroxidation product, protects against acute ischemia/reperfusion injury and chronic heart failure. However, time-dependent changes in ALDH2 profile, aldehydic

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Global Trade Item Number

SKU	GTIN
G2140-250MG	04061833628690
G2140-1G	04061833628683
G2140-5G	04061833628706