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Merck
CN

I0899

Imipramine hydrochloride

BioXtra, ≥99% (TLC)

Synonym(s):

10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride, 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C19H24N2 · HCl
CAS Number:
Molecular Weight:
316.87
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
204-030-7
MDL number:
Assay:
≥99% (TLC)
Form:
powder
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product line

BioXtra

assay

≥99% (TLC)

form

powder

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

solubility

H2O: 50 mg/mL, colorless to faintly yellow

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

SMILES string

Cl[H].CN(C)CCCN1c2ccccc2CCc3ccccc13

InChI

1S/C19H24N2.ClH/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21;/h3-6,8-11H,7,12-15H2,1-2H3;1H

InChI key

XZZXIYZZBJDEEP-UHFFFAOYSA-N

Gene Information

Application


  • Novel, fast, and reliable electrochemical dsDNA biosensor based on O-terminated pristine nanocrystalline boron-doped diamond electrode for DNA interaction studies.: Research featuring a novel electrochemical dsDNA biosensor that facilitates the study of DNA interactions with imipramine hydrochloride, enhancing our understanding of its genotoxic effects and providing crucial insights for biochemistry applications (Augustín M et al., 2024).

  • Comparison of two pharmacological protocols for inducing ex copula ejaculation in donkeys.: In this comparative study, imipramine hydrochloride is used within a pharmacological protocol, offering significant insights into veterinary applications and animal reproductive studies (Khan FA et al., 2024).

  • Development of Visible Spectrophotometric Methods for the Determination of Tricyclic Antidepressants Based on Formation of Molecular Complexes with p-Benzoquinones.: This publication outlines a novel spectrophotometric method for analyzing tricyclic antidepressants like imipramine hydrochloride, providing an efficient tool for quantitative analysis in pharmaceutical and clinical research (Ciuca MD et al., 2023).

Biochem/physiol Actions

Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters with Kis of 7.7 nM and 67 nM, respectively. Has little effect on the dopamine transporter (Ki = 25 μM).
Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters; has little effect on the dopamine transporter.


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pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable



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