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Merck
CN

I1010

IgA from human colostrum

reagent grade, ≥95%, essentially salt-free, lyophilized powder

Synonym(s):

Human IgA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Conjugate:
unconjugated
Species reactivity:
-
Application:
Citations:
11
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conjugate

unconjugated

Quality Level

grade

reagent grade

assay

≥95%

form

essentially salt-free, lyophilized powder

storage temp.

2-8°C

General description

IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears, colostrum and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces
Human IgA is purified from pooled normal human colostrum by fractionation and ion-exchange fractionation.

Application

Purified IgA may be used as a reference antigen, standard, blocking agent or coating protein in a variety of immunoassays including ELISA, dot immunobinding, immunoblotting, immunodiffusion and immunoelectrophoresis. Other applications include starting materials for the preparation of immunogens and solidphase immunoadsorbents. IgA from human colostrum was used as a standard in ELISA (1 mg/ml) and gel electrophoresis.

Preparation Note

Reconstitute with buffered saline (150 mM sodium chloride).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

This item has



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Related Content


A M Bakker-Zierikzee et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 17(2), 134-140 (2006-04-19)
Secretory immunoglobulin A (SIgA) plays an important role in the defence of the gastrointestinal tract. The level of faecal SIgA antibody is associated with increased neutralization and clearance of viruses. Formula-fed infants who lack the transfer of protective maternal SIgA
P Kosuwon et al.
Beneficial microbes, 9(4), 541-552 (2018-04-11)
Little is known about the impact of nutrition on toddler gut microbiota. The plasticity of the toddler gut microbiota indicates that nutritional modulation beyond infancy could potentially impact its maturation. The objective of this study was to determine the effect
Hannah Karen Mina Labayo et al.
EClinicalMedicine, 27, 100561-100561 (2020-10-13)
Norovirus (NV) causes acute gastroenteritis in infants. Humoral and fecal immunoglobulin A (IgA) responses have been correlated with protection against NV; however, the role of breast milk IgA against NV infection and associated diarrhea is still unknown. This study aimed



Global Trade Item Number

SKUGTIN
I1010-5MG04061833847381
I1010-25MG04061833847374